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TRMT10C Knockout Cell Lines

Gene: TRMT10C

Official Full Name: tRNA methyltransferase 10C, mitochondrial RNase P subunitprovided by HGNC

Gene Summary: This gene encodes the precursor of a subunit of the mitochondrial ribonuclease P, which is involved in 5' processing of mitochondrial tRNAs. The encoded protein may confer RNA-binding capacity to mitochondrial ribonuclease P and may be essential for transcript processing, RNA modification, translation and mitochondrial respiration. [provided by RefSeq, Nov 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04463 TRMT10C Knockout cell line (HeLa) Human TRMT10C 1:3~1:6 Negative Online Inquiry
KO04464 TRMT10C Knockout cell line (HCT 116) Human TRMT10C 1:2~1:4 Negative Online Inquiry
KO04465 TRMT10C Knockout cell line (HEK293) Human TRMT10C 1:3~1:6 Negative Online Inquiry

Background

TRMT10C Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically disable the TRMT10C gene, which encodes a crucial enzyme involved in the modification of tRNA molecules. This modification plays a significant role in the regulation of protein synthesis and cellular metabolism. By employing CRISPR-Cas9 gene editing technology, these knockout cell lines facilitate the investigation of the TRMT10C gene's functions, particularly in the context of cellular growth, stress response, and differentiation processes.

The primary mechanism by which TRMT10C influences cellular activities is through its role in the biogenesis and modification of tRNA, which is essential for accurate translation and function of the proteome. By generating cell lines that lack TRMT10C, researchers can explore the downstream effects on protein synthesis and the broader implications for cellular health and disease states, including possible links to cancer and neurodegenerative disorders.

The scientific importance of TRMT10C Gene Knockout Cell Lines lies in their capacity to advance our understanding of gene function and its pathological consequences. These models are invaluable for elucidating the molecular mechanisms underlying various diseases and for testing potential therapeutic strategies. In clinical research, they provide insights into the role of tRNA modifications in human health, potentially aiding in the identification of novel biomarkers or therapeutic targets.

Compared to alternative models that may provide limited or variable results, TRMT10C Gene Knockout Cell Lines offer specificity and consistency, faithfully recapitulating the absence of the TRMT10C gene. This specificity allows researchers to draw more accurate conclusions regarding gene function and its associated pathways.

Researchers and clinicians will benefit significantly from these products, as they not only enhance basic and applied research capabilities but also provide a reliable platform for drug discovery and validation. The potential for breakthroughs in understanding genetic disorders and developing targeted therapies makes TRMT10C Gene Knockout Cell Lines an essential tool in today's biological research landscape.

Our company specializes in providing high-quality, genetically modified cell lines, backed by extensive scientific expertise and a commitment to excellence in research tools. With a focus on advancing scientific understanding, we strive to empower researchers in their quest for innovative solutions in molecular biology and biomedicine.

Please note that all services are for research use only. Not intended for any clinical use.

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