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TOR2A Knockout Cell Lines

Gene: TOR2A

Official Full Name: torsin family 2 member Aprovided by HGNC

Gene Summary: This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity. [provided by RefSeq, Nov 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27600 TOR2A Knockout cell line (HeLa) Human TOR2A 1:3~1:6 Negative Online Inquiry
KO27601 TOR2A Knockout cell line (HCT 116) Human TOR2A 1:2~1:4 Negative Online Inquiry
KO27602 TOR2A Knockout cell line (HEK293) Human TOR2A 1:3~1:6 Negative Online Inquiry
KO27603 TOR2A Knockout cell line (A549) Human TOR2A 1:3~1:4 Negative Online Inquiry

Background

TOR2A Gene Knockout Cell Lines are genetically engineered cell lines designed to provide researchers with powerful tools for studying the functions of the TOR2A gene, which is implicated in various cellular processes including growth regulation, metabolism, and developmental pathways. These cell lines have been meticulously developed using CRISPR/Cas9 technology, enabling precise and efficient knockout of the TOR2A gene, resulting in a cellular model that mimics the loss-of-function context in a controlled laboratory setting.

The primary mechanism of the TOR2A gene's biological role involves its crucial contribution to the Tor signaling pathway, which regulates cell growth and proliferation in response to nutrient availability. By utilizing TOR2A Gene Knockout Cell Lines, researchers can investigate the downstream effects of TOR2A deficiency, including alterations in cellular signaling, metabolic changes, and implications in disease models such as cancer and metabolic disorders.

The scientific importance of these cell lines extends into various research avenues, making them invaluable in both fundamental and applied science. In biomedical research, they can aid in drug discovery processes by enabling the identification of potential therapeutic targets. Clinically, understanding the role of TOR2A may guide the development of interventions to ameliorate diseases associated with dysregulated cell growth.

What sets TOR2A Gene Knockout Cell Lines apart from conventional models is their high specificity and reliability, coupled with an ease of use that accelerates experimental timelines. By removing the complexity of off-target effects typically seen in other gene-editing methods, these cell lines provide consistency and reproducibility in experimental outputs, significantly enhancing the quality of scientific data.

For researchers, clinicians, and biotech companies, the TOR2A Gene Knockout Cell Lines present an unparalleled opportunity to advance their knowledge and applications in the field. They embody both innovation and quality that underscore our commitment to providing cutting-edge biological research products. Our company has a proven track record in developing state-of-the-art genetic tools and is dedicated to supporting scientific discovery with robust, high-performance resources.

Please note that all services are for research use only. Not intended for any clinical use.

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