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TNFSF18 Knockout Cell Lines

Gene: TNFSF18

Official Full Name: TNF superfamily member 18provided by HGNC

Gene Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00243 TNFSF18 Knockout cell line (HCT 116) Human TNFSF18 1:2~1:4 Negative Online Inquiry

Background

TNFSF18 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for the investigation of tumor necrosis factor superfamily member 18 (TNFSF18) functions. These cell lines exhibit a targeted disruption of the TNFSF18 gene, which encodes for a ligand that plays a pivotal role in immune responses and inflammation modulation. By removing the gene's expression, researchers can precisely study the implications of TNFSF18 signaling pathways in various biological contexts.

The unique mechanisms at play within TNFSF18 knockout cells involve altered immune cell signaling and potential shifts in cell proliferation and differentiation pathways. These modifications allow for in-depth analyses of TNFSF18's role in inflammation, autoimmune diseases, and cancer progression. With the growing interest in manipulating immune response mechanisms, these knockout cell lines become invaluable for both basic and applied research.

In the scientific realm, TNFSF18 knockouts hold significant promise for advancing our understanding of immune-related mechanisms, making them particularly useful in the development of new therapeutic strategies. Clinically, findings from experiments utilizing these cell lines could lead to novel interventions for immune disorders, offering a pathway to improved treatment modalities.

Compared to traditional methods of gene editing, such as CRISPR or siRNA, TNFSF18 Gene Knockout Cell Lines provide a stable and consistent model for long-term studies, minimizing variability and enhancing reproducibility. Their robust nature enables researchers to achieve clearer, more precise experimental outcomes.

For researchers and clinicians aiming to delve into the complexities of immune response and therapeutic development, TNFSF18 Gene Knockout Cell Lines offer an unparalleled resource. Our company, recognized for its dedication to high-quality biological products, provides comprehensive support and expertise to facilitate impactful research solutions. By leveraging these innovative cell lines, users can enhance their studies and accelerate discoveries that hold the potential to transform healthcare outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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