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TNFAIP8 Knockout Cell Lines

Gene: TNFAIP8

Official Full Name: TNF alpha induced protein 8provided by HGNC

Gene Summary: Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in positive regulation of apoptotic process. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28777 TNFAIP8 Knockout cell line (HeLa) Human TNFAIP8 1:3~1:6 Negative Online Inquiry
KO28778 TNFAIP8 Knockout cell line (HCT 116) Human TNFAIP8 1:2~1:4 Negative Online Inquiry
KO28779 TNFAIP8 Knockout cell line (HEK293) Human TNFAIP8 1:3~1:6 Negative Online Inquiry
KO28780 TNFAIP8 Knockout cell line (A549) Human TNFAIP8 1:3~1:4 Negative Online Inquiry

Background

TNFAIP8 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating the functional roles of the TNFAIP8 gene, which is implicated in various cellular processes including apoptosis, inflammation, and cancer progression. These cell lines are engineered through targeted genome editing techniques, such as CRISPR-Cas9, to precisely inactivate the TNFAIP8 gene, allowing scientists to analyze the phenotypic and molecular consequences of its absence in a controlled environment.

The primary function of these knockout cell lines lies in their ability to facilitate the study of TNFAIP8's involvement in signaling pathways associated with tumor growth and immune responses. By comparing knockout cells to their wild-type counterparts, researchers can elucidate the gene’s impact on growth rates, cellular morphology, and resistance to stressors, among other critical parameters. This provides invaluable insights into how TNFAIP8 may contribute to disease mechanisms, especially in oncology and autoimmune disorders.

In research and clinical settings, TNFAIP8 Gene Knockout Cell Lines hold significant scientific importance, as they can aid in the identification of novel therapeutic targets and enhance our understanding of complex diseases. The data generated using these models can be pivotal for drug discovery and validation, particularly in the development of targeted therapies aimed at cancers where TNFAIP8 plays a crucial role.

What sets these knockout cell lines apart from traditional models is their high specificity and reproducibility, ensuring that findings are robust and translatable. Additionally, they offer flexibility for downstream applications, including drug response assays, gene expression analyses, and protein interaction studies. Researchers and clinicians can therefore rely on these cell lines for more precise experimental designs and outcomes.

The value of TNFAIP8 Gene Knockout Cell Lines to the scientific community is further amplified by our company’s long-standing expertise in cellular models and gene editing technologies. With a commitment to quality and innovation, we provide these unique tools, empowering researchers to advance their work and contribute meaningfully to the field of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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