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TMEM87B Knockout Cell Lines

Gene: TMEM87B

Official Full Name: transmembrane protein 87Bprovided by HGNC

Gene Summary: This gene encodes a protein that may interact with human papillomavirus type 18 E6 oncogene. The protein is also likely to be involved in endosome-to-trans-Golgi network retrograde transport. The gene is expressed in adult and fetal tissues, including brain and heart. This gene is a component of the 2q13 deletion syndrome. Mutations in this gene may be associated with congenital heart defects. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24498 TMEM87B Knockout cell line (HeLa) Human TMEM87B 1:3~1:6 Negative Online Inquiry
KO24499 TMEM87B Knockout cell line (HCT 116) Human TMEM87B 1:2~1:4 Negative Online Inquiry
KO24500 TMEM87B Knockout cell line (HEK293) Human TMEM87B 1:3~1:6 Negative Online Inquiry
KO24501 TMEM87B Knockout cell line (A549) Human TMEM87B 1:3~1:4 Negative Online Inquiry

Background

TMEM87B Gene Knockout Cell Lines represent a significant innovation in the field of molecular biology, specifically tailored for researchers focused on gene function and cellular processes. These cell lines are engineered to exhibit a complete knockout of the TMEM87B gene, a component implicated in various cellular signaling pathways, including those responsible for cellular homeostasis, proliferation, and differentiation. By removing the TMEM87B gene, these cell lines serve as a robust tool for assessing the functional outcomes of gene loss on cellular behavior.

The primary mechanism of action behind these knockout cell lines involves CRISPR-Cas9 gene-editing technology, which allows for precise and targeted genetic modifications. Using this technique, researchers can delve into the biological consequences of TMEM87B absence, investigating phenotypic changes, alterations in signaling pathways, and potential compensatory mechanisms activated in response to gene knockout. This depth of analysis is invaluable for unveiling the gene's role in various physiological and pathological conditions.

Scientifically, TMEM87B Gene Knockout Cell Lines hold immense relevance in both basic and applied research. Their utility extends into fields such as cancer research, neurobiology, and developmental biology, offering insights that can lead to advancements in therapeutic approaches and drug development. Researchers and clinicians can leverage these cell lines to understand disease mechanisms at a molecular level, laying the groundwork for novel interventions.

What sets our TMEM87B Gene Knockout Cell Lines apart from other products on the market is our commitment to quality and functionality; they are meticulously validated for consistent performance and reproducibility. Unlike existing alternatives that may lack specificity or have variable knockout efficiency, our cell lines ensure reliable outcomes, saving valuable time and resources in experimental design.

The value of TMEM87B Gene Knockout Cell Lines to researchers and clinicians alike cannot be overstated. They provide a unique platform to explore essential biological questions, enhance the understanding of TMEM87B's role in disease, and ultimately contribute to the development of targeted therapies. With extensive expertise in genetic engineering and a robust portfolio of high-quality biological products, our company stands at the forefront of enabling scientific discovery, making these cell lines a pivotal addition to any research toolkit.

Please note that all services are for research use only. Not intended for any clinical use.

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