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TMEM221 Knockout Cell Lines

Gene: TMEM221

Official Full Name: transmembrane protein 221provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13204 TMEM221 Knockout cell line (HCT 116) Human TMEM221 1:2~1:4 Negative Online Inquiry
KO13205 TMEM221 Knockout cell line (HEK293) Human TMEM221 1:3~1:6 Negative Online Inquiry

Background

TMEM221 Gene Knockout Cell Lines are a cutting-edge tool for researchers investigating the specific roles of the TMEM221 gene in cellular processes. These genetically modified cell lines feature a targeted gene knockout, achieved through advanced CRISPR-Cas9 technology, which effectively disrupts the function of the TMEM221 protein. This disruption allows for a comprehensive study of the gene's influence on various biological pathways, particularly those pertinent to cell signaling, proliferation, and apoptosis.

The primary mechanism of TMEM221 Gene Knockout Cell Lines hinges on the concept of gene inactivation, which enables scientists to discern the consequences of eliminating TMEM221 function. This offers a unique platform for exploring how alterations in TMEM221 expression impact cellular behavior and may lead to elucidations of associated pathophysiological conditions, including potential ramifications in cancer biology and neurodevelopmental disorders.

In terms of scientific significance, these cell lines serve as invaluable assets in both research laboratories and clinical settings, facilitating a deeper understanding of gene function and gene-gene interactions. Their application is particularly relevant in drug discovery processes, where elucidating the role of target genes like TMEM221 can guide the design of therapeutic strategies and biomarkers.

Compared to alternative methods, such as traditional knockdown techniques utilizing siRNAs, TMEM221 Gene Knockout Cell Lines provide a more permanent and comprehensive approach to gene inactivation. This permanent knockout can yield more consistent results and reduce variability inherent in transient knockdown models, ensuring that research findings are both robust and reproducible.

For researchers and clinicians seeking to explore the functional implications of the TMEM221 gene, these knockout cell lines represent a pivotal resource that can enhance the overall understanding of gene function in health and disease. Our company specializes in the development of innovative genetic tools, empowering the scientific community through high-quality products tailored to accelerate biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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