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TMEM116 Knockout Cell Lines

Gene: TMEM116

Official Full Name: transmembrane protein 116provided by HGNC

Gene Summary: Predicted to be involved in signal transduction. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23898 TMEM116 Knockout cell line (HeLa) Human TMEM116 1:3~1:6 Negative Online Inquiry
KO23899 TMEM116 Knockout cell line (HCT 116) Human TMEM116 1:2~1:4 Negative Online Inquiry
KO23900 TMEM116 Knockout cell line (HEK293) Human TMEM116 1:3~1:6 Negative Online Inquiry
KO23901 TMEM116 Knockout cell line (A549) Human TMEM116 1:3~1:4 Negative Online Inquiry

Background

TMEM116 Gene Knockout Cell Lines are specialized genetically engineered cell lines designed to facilitate the study of the TMEM116 gene's functional role in cellular processes. By creating a knockout of the TMEM116 gene, these cell lines allow researchers to observe the consequences of its absence, thereby elucidating the gene’s contributions to various biological pathways, including cell signaling, metabolism, and disease mechanisms.

The functionality of the TMEM116 gene knockout cell lines is rooted in the precise CRISPR-Cas9 gene-editing technology employed to generate them. This technology enables targeted gene disruption, leading to the permanent loss of TMEM116 expression. The resulting cell lines provide a robust system for studying the gene's involvement in fundamental biological processes and its implications in pathological conditions, such as cancer and neurodegenerative diseases. Researchers can assess phenotypic changes, signaling pathway alterations, and interactions with other biomolecules, facilitating deeper insights into the biological roles of TMEM116.

The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. In basic research, they serve as pivotal tools for investigating gene function and regulation, while in translational research, they help to identify potential therapeutic targets. The ability to study the effects of gene knockout in a controlled environment enhances the understanding of gene-disease associations and fosters the development of innovative treatment strategies.

Compared to traditional knockout methods, which can be time-consuming and less precise, TMEM116 Gene Knockout Cell Lines offer a streamlined solution for researchers. Their utility accelerates experimental timelines and increases reproducibility, making them an attractive option for labs focused on gene function studies.

For researchers, clinicians, and pharmaceutical companies, the TMEM116 Gene Knockout Cell Lines represent a valuable asset in the pursuit of scientific discovery and therapeutic innovation. These cell lines exemplify the cutting-edge advancements in genetic research, allowing for novel experiments that could lead to significant breakthroughs in understanding molecular biology and disease treatment.

Our company stands at the forefront of genetic research tools, dedicated to providing high-quality, reliable biological products that empower scientists and clinicians to achieve their research goals efficiently and effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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