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TCF15 Knockout Cell Lines

Gene: TCF15

Official Full Name: transcription factor 15provided by HGNC

Gene Summary: The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35090 TCF15 Knockout cell line (HEK293) Human TCF15 1:3~1:6 Negative Online Inquiry

Background

TCF15 Gene Knockout Cell Lines are highly engineered cellular models designed to study the specific roles of the TCF15 gene in various biological processes. TCF15 (T-cell factor 15) is a transcription factor that plays a critical role in cellular differentiation and development, particularly in the regulation of embryonic stem cell pluripotency and lineage commitment. These knockout cell lines allow researchers to observe the effects of the gene's absence, enabling deeper insights into its regulatory functions and downstream signaling pathways.

The primary mechanism of action for these knockout cell lines involves the targeted deletion of the TCF15 gene using advanced CRISPR-Cas9 gene-editing technology. By disrupting the gene, the resultant cell lines facilitate the investigation of phenotypic changes, gene expression alterations, and cellular behaviors that manifest in the absence of TCF15. This technology supports a myriad of applications, from understanding development and differentiation to investigating disease mechanisms, such as cancer and metabolic disorders.

The scientific importance of TCF15 knockout models is evident in both basic and applied research, where understanding transcriptional regulation is paramount. They offer a robust platform for functional studies that can lead to breakthroughs in therapeutic strategies or biomarker identification. Compared to other methods, such as traditional RNA interference or overexpression approaches, the knockout lines provide a complete absence of the target gene, allowing for a more comprehensive analysis of its function.

Researchers and clinicians who utilize TCF15 Gene Knockout Cell Lines gain a distinct advantage in their studies, with reliable data generated from a high-fidelity model system. These cell lines not only streamline workflows in genetic studies but also enhance reproducibility and specificity in experimental outcomes, ultimately accelerating the pace of discovery in various fields.

Our company is committed to providing cutting-edge biological products that empower researchers to address complex scientific questions. With an emphasis on quality and innovation, our TCF15 Gene Knockout Cell Lines exemplify our dedication to supporting impactful research and advancing the frontiers of bioscience.

Please note that all services are for research use only. Not intended for any clinical use.

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