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TBRG4 Knockout Cell Lines

Gene: TBRG4

Official Full Name: transforming growth factor beta regulator 4provided by HGNC

Gene Summary: Enables RNA binding activity. Involved in mitochondrial mRNA processing and regulation of mitochondrial mRNA stability. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33421 TBRG4 Knockout cell line (HeLa) Human TBRG4 1:3~1:6 Negative Online Inquiry
KO33422 TBRG4 Knockout cell line (HCT 116) Human TBRG4 1:2~1:4 Negative Online Inquiry
KO33423 TBRG4 Knockout cell line (HEK293) Human TBRG4 1:3~1:6 Negative Online Inquiry
KO33424 TBRG4 Knockout cell line (A549) Human TBRG4 1:3~1:4 Negative Online Inquiry

Background

TBRG4 Gene Knockout Cell Lines are expertly designed cellular models that have been genetically modified to disrupt the function of the TBRG4 gene, a critical regulator of various cellular processes including apoptosis, proliferation, and differentiation. By employing advanced CRISPR/Cas9 genome editing technology, these knockout cell lines allow researchers to investigate the specific roles of the TBRG4 gene in disease mechanisms and cellular signaling pathways, effectively providing a powerful tool for elucidating gene function.

The primary mechanism by which TBRG4 Gene Knockout Cell Lines operate involves the complete inactivation of TBRG4 expression, leading to a range of phenotypic changes that can be quantitatively assessed. This disruption not only aids in understanding how the loss of TBRG4 impacts cell behavior but also enables the exploration of potential compensatory mechanisms in signaling pathways. Such insights are invaluable for informing therapeutic strategies aimed at diseases where TBRG4 dysfunction is implicated, including certain cancers and metabolic disorders.

Scientifically, the TBRG4 Gene Knockout Cell Lines hold immense significance for both basic and translational research. Researchers can utilize these cell lines to screen for new therapeutic compounds, validate drug targets, and study disease pathology in a controlled environment. In clinical contexts, insights gleaned from these studies can lead to the development of precision medicine approaches tailored to specific genetic profiles.

Unlike traditional knockout models that may sometimes exhibit incomplete gene disruption or compensatory upregulation of related genes, the TBRG4 Gene Knockout Cell Lines provide a highly efficient, reproducible, and precise tool for gene function studies. This clarity in genetic manipulation, combined with the rapid generation and characterization of the cell lines, set our offering apart from competitors.

For researchers and clinicians aiming to deepen their understanding of gene functionality and its implications in health and disease, TBRG4 Gene Knockout Cell Lines represent a valuable asset. Our company specializes in providing high-quality genetic tools and resources, underpinned by extensive expertise in molecular biology and genetic engineering. We are dedicated to supporting the research community with innovative products that propel scientific discovery and therapeutic advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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