Gene: TAS2R20
Official Full Name: taste 2 receptor member 20provided by HGNC
Gene Summary: This gene encodes a member of the taste receptor two family of class C G-protein coupled receptors. Receptors of this family have a short extracellular N-terminus, seven transmembrane helices, three extracellular loops and three intracellular loops, and an intracellular C-terminus. Members of this family are expressed in a subset of taste receptor cells, where they function in bitter taste reception, as well as in non-gustatory cells including those of the brain, reproductive organs, respiratory system, and gastrointestinal system. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13583 | TAS2R20 Knockout cell line (HeLa) | Human | TAS2R20 | 1:3~1:6 | Negative | Online Inquiry |
KO13584 | TAS2R20 Knockout cell line (HCT 116) | Human | TAS2R20 | 1:2~1:4 | Negative | Online Inquiry |
KO13585 | TAS2R20 Knockout cell line (A549) | Human | TAS2R20 | 1:3~1:4 | Negative | Online Inquiry |
TAS2R20 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TAS2R20 gene, which encodes for one of the bitter taste receptors involved in the gustatory signaling pathways. These cell lines are pivotal in investigating the biological mechanisms of taste perception, specifically how variations in the TAS2R20 gene influence physiological responses to bitter compounds.
The primary function of TAS2R20 Gene Knockout Cell Lines is to facilitate research into bitter taste signaling and its implications in several physiological processes, including appetite regulation, metabolic pathways, and potential therapeutic interventions in metabolic disorders. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide a robust platform for studying the absence of TAS2R20, enabling researchers to dissect its role in cellular responses to bitter substances and the complex interplay between taste perception and health.
Scientifically, these cell lines are invaluable for both basic and applied research. In clinical settings, they can aid in understanding the genetic basis of taste sensitivity variations among individuals and their correlation with health outcomes, such as obesity and cardiovascular diseases. The TAS2R20 Gene Knockout Cell Lines offer researchers the opportunity to explore novel therapeutic strategies targeting the bitter taste receptor pathways, thus expanding the horizons of nutritional science and drug development.
What sets these cell lines apart from alternative models is their precision in genetic modification, allowing for reproducibility and consistency in experiments. They bridge the gap between genetic research and practical applications, providing a focused tool for researchers aiming to contribute significantly to the fields of nutrition, pharmacology, and genetics.
This product is essential for researchers and clinicians aiming to harness the power of taste perception in their work. It represents a commitment to advancing understanding in the scientific community, enhancing the quality of research and enabling groundbreaking discoveries.
Our company specializes in developing cutting-edge biological products, providing researchers with tools that are not only reliable but also pivotal in driving innovation and exploration within the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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