Gene: TAS2R10
Official Full Name: taste 2 receptor member 10provided by HGNC
Gene Summary: This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23287 | TAS2R10 Knockout cell line (HeLa) | Human | TAS2R10 | 1:3~1:6 | Negative | Online Inquiry |
TAS2R10 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the implications and functionalities of the TAS2R10 gene in human physiology and taste biochemistry. The TAS2R10 gene encodes for a receptor that plays a crucial role in bitter taste perception, significantly influencing dietary choices and potential gene-environment interactions related to taste and nutrition. These knockout cell lines provide researchers with a unique platform to investigate the physiological processes associated with TAS2R10, enabling the exploration of its impact on metabolic pathways and sensory biology.
The primary mechanism of action involves the complete disruption of the TAS2R10 gene, creating a cellular environment where the receptor is absent. This allows for the dissection of the downstream signaling pathways and physiological responses in the absence of bitter taste stimulation. The resulting data can be invaluable for understanding how variations in bitter taste receptors can affect overall health, preferences for certain food compounds, and even therapeutic outcomes for patients with varying genetic backgrounds.
The scientific importance of TAS2R10 Gene Knockout Cell Lines extends beyond taste perception; these models are pivotal in pharmacogenomics, nutrition research, and the development of personalized dietary recommendations. In clinical settings, they can assist in investigating how genetic variations in taste receptors impact drug metabolism and efficacy, paving the way for tailored therapeutic strategies.
When compared to alternative cell line models, TAS2R10 knockout lines offer enhanced specificity and relevance for studies on bitter taste mechanisms. Their genetic modification allows researchers to achieve precise, reproducible results, overcoming the limitations often encountered in wild-type models.
For researchers, clinicians, and scientists, the availability of TAS2R10 Gene Knockout Cell Lines is a significant asset. By utilizing these specialized lines, they can accelerate their discoveries regarding taste biology and its relationship with broader metabolic and health outcomes.
At our company, we pride ourselves on our comprehensive expertise in creating advanced biological models, ensuring that our products meet the highest standards of quality and relevance for cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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