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TAC1 Knockout Cell Lines

Gene: TAC1

Official Full Name: tachykinin precursor 1provided by HGNC

Gene Summary: This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07362 TAC1 Knockout cell line (HEK293) Human TAC1 1:3~1:6 Negative Online Inquiry

Background

TAC1 Gene Knockout Cell Lines are engineered cellular models that have undergone targeted gene deletion of the tachykinin precursor 1 (TAC1) gene, which encodes for neuropeptides critical in various physiological roles, particularly in pain modulation and stress responses. These cell lines serve as vital tools for investigating the functional implications of TAC1 deficiency in various biological processes, enabling researchers to dissect the intricate pathways associated with neuropeptide signaling.

The key function of TAC1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for assessing the physiological and pathophysiological roles of TAC1-derived peptides, such as Substance P. By eliminating the TAC1 gene, researchers can analyze the resultant alterations in cellular function, receptor interaction, and signaling cascades that may underpin pain and anxiety disorders, among others. The use of these knockout models facilitates high-throughput screening of potential pharmacological agents, offering insights into novel therapeutic approaches.

Scientifically, the relevance of TAC1 Gene Knockout Cell Lines extends to various research domains, including neurobiology, pharmacology, and developmental biology. They enable clinicians and researchers to model diseases where tachykinin signaling is implicated, providing a foundation for understanding conditions such as chronic pain syndromes, depression, and stress-related disorders.

What sets TAC1 Gene Knockout Cell Lines apart from alternatives is their precise gene editing using CRISPR/Cas9 technology, ensuring a high degree of specificity and reproducibility. Unlike traditional cell lines with unpredictable genetic backgrounds, these knockout models provide researchers with a stable and consistent biological platform that enhances the reliability of experimental outcomes.

For researchers and clinicians alike, TAC1 Gene Knockout Cell Lines represent an invaluable asset in the quest to identify and validate novel therapeutic targets. They allow for a deeper understanding of the physiological underpinnings of complex disorders, thus paving the way for innovative treatments.

At [Your Company Name], we take pride in our commitment to excellence in providing high-quality biological products. With a strong focus on innovation and reliability, our TAC1 Gene Knockout Cell Lines stand as a testament to our expertise in advancing research in the life sciences, driving forward critical discoveries that can transform clinical practice.

Please note that all services are for research use only. Not intended for any clinical use.

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