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SYPL2 Knockout Cell Lines

Gene: SYPL2

Official Full Name: synaptophysin like 2provided by HGNC

Gene Summary: Involved in substantia nigra development. Predicted to be located in membrane and synaptic vesicle. Predicted to be active in synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13608 SYPL2 Knockout cell line (HCT 116) Human SYPL2 1:2~1:4 Negative Online Inquiry
KO13609 SYPL2 Knockout cell line (HEK293) Human SYPL2 1:3~1:6 Negative Online Inquiry

Background

SYPL2 Gene Knockout Cell Lines are specialized cellular models engineered to specifically disrupt the expression of the SYPL2 gene, a key player in intracellular trafficking and signaling pathways. This genetic modification allows researchers to investigate the resultant cellular behaviors and phenotypic changes, thereby elucidating the role of SYPL2 in various biological processes.

These cell lines operate by utilizing the CRISPR-Cas9 genome editing technology to create specific and targeted interruptions in the SYPL2 gene sequence. The resulting knockout cells exhibit a comprehensive loss of SYPL2 protein function, enabling detailed studies on its physiological roles in cellular communication, neurodevelopment, and potential implications in diseases such as cancer and neurological disorders. The mechanisms of action facilitated by the SYPL2 gene knockout can provide insights into how disruptions in this gene's function can lead to aberrant cellular processes.

The scientific importance of SYPL2 Gene Knockout Cell Lines lies in their diverse applications in both research and clinical settings. These models are invaluable in drug discovery, efficacy testing, and understanding disease mechanisms, allowing researchers to approach therapeutic development from a genetically-defined perspective. Compared to traditional cell lines, which may exhibit background expression of SYPL2, the knockout cell lines provide a clean slate for experiments, minimizing confounding variables and increasing the reliability of experimental results.

The specific advantages of utilizing SYPL2 Gene Knockout Cell Lines include the high precision of CRISPR technology, reduced off-target effects, and the ability to generate stable lines that can be easily expanded for long-term studies. These attributes make them an essential tool for researchers aiming to dissect complex biological pathways with a rigorous, controlled approach.

For researchers and clinicians, the value of these knockout cell lines extends beyond the novelty of genetic manipulation; they represent a powerful means to explore the intricacies of gene function in a reproducible manner, driving forward our understanding of translational research and potential clinical applications. Our company specializes in developing high-quality gene-editing tools and cellular models and stands by its commitment to providing leading-edge products that support the advancement of biological research and healthcare innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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