Gene: SYCP2L
Official Full Name: synaptonemal complex protein 2 likeprovided by HGNC
Gene Summary: Predicted to be involved in meiotic recombination checkpoint signaling and synaptonemal complex assembly. Predicted to act upstream of or within negative regulation of programmed cell death. Located in condensed chromosome, centromeric region and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27424 | SYCP2L Knockout cell line (HCT 116) | Human | SYCP2L | 1:2~1:4 | Negative | Online Inquiry |
KO27425 | SYCP2L Knockout cell line (HEK293) | Human | SYCP2L | 1:3~1:6 | Negative | Online Inquiry |
KO27426 | SYCP2L Knockout cell line (A549) | Human | SYCP2L | 1:3~1:4 | Negative | Online Inquiry |
SYCP2L Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the biological role of the SYCP2L gene, which is vital in the processes of meiosis and gametogenesis. These knockout cell lines provide researchers with a powerful tool to understand the precise mechanisms by which SYCP2L influences chromosomal behavior during cell division, particularly in the formation of gametes.
Mechanistically, the SYCP2L gene is crucial for the assembly and stability of the synaptonemal complex during meiosis, facilitating homologous chromosome pairing and recombination. By utilizing these knockout cell lines, researchers can study the resultant phenotypic changes, gene expression profiles, and protein interactions that occur when SYCP2L function is disrupted. This offers invaluable insights into fertility-related disorders and chromosomal abnormalities, thus emphasizing the significance of SYCP2L within reproductive biology.
In clinical and research settings, these SYCP2L knockout cell lines can be utilized to model human diseases linked to chromosomal missegregation and reproductive failure, paving the way for the development of targeted therapeutics. Their availability enhances the capacity to conduct high-throughput screening for pharmaceuticals that may restore normal function in SYCP2L-deficient cells, establishing a potential breakthrough in reproductive health management.
What sets SYCP2L Gene Knockout Cell Lines apart from alternatives is both the specificity of the gene knockout and the ease of use offered by our proprietary cell culture protocols. This leads to more reproducible results and decreases the time and resources needed for experimental validation. The cell lines are also compatible with a range of assays, from molecular to cellular, making them highly versatile for varied research applications.
For researchers and clinicians focused on advancing reproductive biology, the SYCP2L Gene Knockout Cell Lines represent a significant technological advancement in the study of gametogenesis and associated disorders. Our company, with its dedicated focus on providing high-quality biological reagents and models, combines expertise with innovative solutions to support your scientific endeavors, ensuring that your research is both impactful and productive.
Please note that all services are for research use only. Not intended for any clinical use.
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