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SVEP1 Knockout Cell Lines

Gene: SVEP1

Official Full Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1provided by HGNC

Gene Summary: Enables integrin binding activity. Involved in negative regulation of vasoconstriction and positive regulation of platelet activation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00068 SVEP1 Knockout cell line (Vips) Human SVEP1 Negative Online Inquiry

Background

SVEP1 Gene Knockout Cell Lines are genetically engineered mammalian cell lines that have had the SVEP1 gene selectively inactivated. SVEP1, or Supervital Extra-Cellular Matrix Protein 1, plays a crucial role in various biological processes, particularly in modulating the extracellular matrix and influencing cell behavior. These knockout cell lines provide researchers with an indispensable tool for studying the functional implications of SVEP1 deprivation in cellular mechanisms, signaling pathways, and disease models.

The key mechanism through which SVEP1 Gene Knockout Cell Lines operate is by removing the expression of the SVEP1 gene, which enables researchers to observe phenotypic changes in cellular growth, migration, adhesion, and differentiation. In doing so, scientists can explore how the absence of this protein influences various cellular processes, particularly in relation to cancer biology, tissue engineering, and regenerative medicine. These insights are critical for understanding conditions such as fibrosis, neurodegenerative diseases, and tumor progression, thereby underscoring their scientific importance.

What sets SVEP1 Gene Knockout Cell Lines apart from other genetic models is their specificity and reliability. Conventional knockdown techniques often result in incomplete silencing or off-target effects, whereas our knockout lines represent a definitive elimination of the SVEP1 gene. This specificity allows for more accurate and reproducible experimental outcomes, providing researchers with confidence in their data.

Furthermore, these cell lines are optimized for various applications, including high-throughput screening, drug testing, and functional assays, making them invaluable for both academic research and clinical applications. The ability to generate a detailed understanding of SVEP1's role in disease mechanisms can facilitate the development of targeted therapies and innovative treatment strategies.

At [Your Company Name], we pride ourselves on our commitment to scientific excellence and innovation. Our team of experts employs cutting-edge genomic technologies to deliver high-quality biological products, including SVEP1 Gene Knockout Cell Lines, that empower researchers and clinicians to advance their work and achieve meaningful breakthroughs in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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