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SUGCT Knockout Cell Lines

Gene: SUGCT

Official Full Name: succinyl-CoA:glutarate-CoA transferaseprovided by HGNC

Gene Summary: This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13651 SUGCT Knockout cell line (HeLa) Human SUGCT 1:3~1:6 Negative Online Inquiry
KO13652 SUGCT Knockout cell line (HCT 116) Human SUGCT 1:2~1:4 Negative Online Inquiry
KO13653 SUGCT Knockout cell line (HEK293) Human SUGCT 1:3~1:6 Negative Online Inquiry
KO13654 SUGCT Knockout cell line (A549) Human SUGCT 1:3~1:4 Negative Online Inquiry

Background

SUGCT Gene Knockout Cell Lines are engineered cellular models that have undergone targeted gene disruption to assess the functional role of the SUGCT gene. These cell lines utilize CRISPR-Cas9 technology to create precise deletions or mutations within the SUGCT gene, allowing researchers to study the consequences of SUGCT loss on various biological processes. Cell lines are invaluable for dissecting biochemical pathways and understanding cellular responses to genetic alterations, making them essential tools in both basic and applied research.

The primary function of SUGCT Gene Knockout Cell Lines lies in their capacity to provide insights into the physiological and pathological roles of the SUGCT gene. Researchers can investigate the implications of SUGCT deficiency on pathways such as metabolism, cell proliferation, and apoptosis. By comparing the behavior of knockout cells to their wild-type counterparts, scientists can elucidate gene function and contribute to a more comprehensive understanding of related diseases, including cancer and metabolic disorders.

The scientific importance of these cell lines extends to numerous applications in research and clinical settings. They facilitate drug discovery efforts by enabling high-throughput screening of therapeutic candidates and target validation studies. Additionally, these cell lines can aid in biomarker discovery and provide models for systems biology approaches, enhancing the understanding of complex diseases at a molecular level.

One of the key advantages of SUGCT Gene Knockout Cell Lines is the specificity and efficiency offered by the CRISPR-Cas9 technology employed in their creation. Unlike traditional methods that may result in off-target effects or incomplete gene knockout, our cell lines provide researchers with reliable, reproducible results, ensuring that experimental outcomes are both accurate and relevant. This precision minimizes experimental variability, enhancing the reliability of downstream applications.

For researchers and clinicians seeking to advance their understanding of SUGCT function and its implications in human health, SUGCT Gene Knockout Cell Lines represent a valuable resource. With our commitment to quality and innovation, our company strives to support the scientific community by providing top-tier biological products that drive discovery and enhance research capabilities. Our expertise in genetic engineering and cell line development ensures that users receive products that meet the highest standards of excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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