Gene: STK35
Official Full Name: serine/threonine kinase 35provided by HGNC
Gene Summary: The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04720 | STK35 Knockout cell line (HeLa) | Human | STK35 | 1:3~1:6 | Negative | Online Inquiry |
KO04721 | STK35 Knockout cell line (HCT 116) | Human | STK35 | 1:2~1:4 | Negative | Online Inquiry |
KO04722 | STK35 Knockout cell line (HEK293) | Human | STK35 | 1:3~1:6 | Negative | Online Inquiry |
KO04723 | STK35 Knockout cell line (A549) | Human | STK35 | 1:3~1:4 | Negative | Online Inquiry |
STK35 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of STK35 (Serine/threonine kinase 35), a gene implicated in various cellular processes, including cell signaling and proliferation. These knockout cell lines are created using advanced CRISPR-Cas9 technology, resulting in cells where the STK35 gene is selectively disrupted. This precise gene editing enables researchers to explore the downstream effects of STK35 absence, enhancing our understanding of its role in normal physiology and disease pathogenesis.
The primary function of STK35 Gene Knockout Cell Lines lies in their ability to mimic the loss of function observed in various disease states, thus providing critical insights into the molecular mechanisms associated with STK35 dysfunction. Such models are invaluable in investigating the gene's involvement in cellular signaling pathways and its effects on cellular behaviors like growth, survival, and differentiation. This capability is particularly vital for researchers aiming to identify potential therapeutic targets for conditions linked to aberrant STK35 signaling.
In terms of scientific importance, these knockout cell lines serve as powerful tools in both basic research and drug development contexts. They enable the examination of gene-gene interactions and the testing of pharmacological agents aimed at modulating STK35 activity. Furthermore, these models can be employed to develop biomarkers for patient stratification in clinical settings, improving personalized medicine approaches.
Comparatively, the STK35 Gene Knockout Cell Lines stand out due to their high specificity and reproducibility, addressing the limitations commonly associated with traditional knockdown techniques that may result in off-target effects. Researchers will find significant value in the precise gene targeting offered by these cell lines, facilitating reproducible experiments that yield meaningful biological data.
Valuable to both researchers and clinicians, these cell lines provide a streamlined approach to elucidating STK35's functional implications, ultimately bridging the gap between bench and bedside. By leveraging these resources, users can accelerate their discoveries and translate their findings into innovative therapeutic strategies.
Our company specializes in providing high-quality biological products tailored for cutting-edge research. With a commitment to excellence and innovation, we ensure that our STK35 Gene Knockout Cell Lines meet the highest standards, empowering scientists to advance their frontline research efforts.
Please note that all services are for research use only. Not intended for any clinical use.
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