Gene: STEAP4
Official Full Name: STEAP4 metalloreductaseprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05405 | STEAP4 Knockout cell line (HeLa) | Human | STEAP4 | 1:3~1:6 | Negative | Online Inquiry |
STEAP4 Gene Knockout Cell Lines are engineered cellular models that provide researchers with the ability to study the role of the STEAP4 gene, which encodes a transmembrane protein believed to play a significant role in cellular differentiation, development, and potentially in various disease states, including cancer. These cell lines enable the precise investigation of gene function through the targeted removal of this gene, allowing for in-depth analyses of cellular mechanisms and pathways affected by STEAP4.
The primary function of these knockout cell lines is to facilitate the examination of STEAP4's involvement in iron metabolism, immune responses, and the regulation of inflammatory processes. By employing techniques such as CRISPR-Cas9 for gene editing, researchers can create stable knockouts that exhibit altered phenotypes, which provide insights into the biological processes mediated by STEAP4. This is invaluable for dissecting complex networks and elucidating the molecular underpinnings of conditions where STEAP4 may be implicated.
In the realm of scientific research and clinical applications, STEAP4 knockout cell lines can be pivotal in drug discovery, functional genomics, and pathology studies. The ability to explore the effects of STEAP4 deficiency on cell signaling and metabolic pathways opens avenues for novel therapeutic targets in diseases where STEAP4 plays a crucial role, thereby enhancing the potential for innovative treatments.
What sets these knockout cell lines apart from other models is their specificity and reliability in representing STEAP4 gene interactions. Unlike traditional methods that may offer limited insights into gene function, our STEAP4 gene knockout cell lines provide a robust platform for elucidating the intricate roles of STEAP4 with high reproducibility and accuracy. Researchers can expect superior customization and detailed phenotypic data, alongside an extensive support network for experimental design and execution.
By using STEAP4 Gene Knockout Cell Lines, researchers and clinicians can gain a clearer understanding of STEAP4's biological significance, which ultimately contributes to the advancement of the field of genetics and therapeutics. Our company, known for its commitment to excellence in biotechnological innovation, provides these high-quality cell lines backed by expert guidance and comprehensive application support, ensuring that your research goals are met with success and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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