Gene: SPINK4
Official Full Name: serine peptidase inhibitor Kazal type 4provided by HGNC
Gene Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27687 | SPINK4 Knockout cell line (HeLa) | Human | SPINK4 | 1:3~1:6 | Negative | Online Inquiry |
SPINK4 Gene Knockout Cell Lines are advanced biological tools specifically engineered to study the functions and regulatory pathways associated with the Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4) gene. This innovative product consists of genetically modified cell lines in which the SPINK4 gene has been inactivated, allowing researchers to investigate the physiological roles of SPINK4 in various biological processes, including inflammation, cancer progression, and tissue repair mechanisms.
The primary function of these knockout cell lines is to elucidate the impact of SPINK4 deficiency on cellular behavior, gene expression changes, and metabolic pathways. By employing CRISPR-Cas9 or other precise gene-editing technologies, SPINK4 Gene Knockout Cell Lines facilitate the dissection of SPINK4’s interaction with serine proteases and its regulatory effects on the extracellular matrix, providing insights into disease mechanisms that are often obscured in the presence of the normal gene.
The scientific significance of SPINK4 Gene Knockout Cell Lines extends into translational research and potential therapeutic developments, particularly in areas such as oncology, gastroenterology, and regenerative medicine. Their utility in functional assays, drug screening, and biomarker discovery reinforces their relevance in both academic and clinical laboratory settings.
What sets these knockout cell lines apart from traditional wild-type models is the ability to deliver a more comprehensive understanding of gene function and interaction networks without interference from SPINK4’s normal activity. This specificity promotes more reliable data and robust experimental outcomes, thus accelerating research timelines and enhancing reproducibility.
For researchers and clinicians aiming to delve into the multifaceted roles of SPINK4, these knockout cell lines represent a valuable asset, enabling ground-breaking discoveries that may translate into clinical advancements. With our established expertise in genetic engineering and cell line development, we provide a reliable source for cutting-edge biological products designed to empower scientific exploration and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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