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SPATA6 Knockout Cell Lines

Gene: SPATA6

Official Full Name: spermatogenesis associated 6provided by HGNC

Gene Summary: Predicted to enable myosin light chain binding activity. Predicted to be involved in motile cilium assembly and spermatogenesis. Predicted to be located in extracellular region and motile cilium. Predicted to be active in sperm head-tail coupling apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21612 SPATA6 Knockout cell line (HCT 116) Human SPATA6 1:2~1:4 Negative Online Inquiry
KO21613 SPATA6 Knockout cell line (HEK293) Human SPATA6 1:3~1:6 Negative Online Inquiry
KO21614 SPATA6 Knockout cell line (A549) Human SPATA6 1:3~1:4 Negative Online Inquiry

Background

SPATA6 Gene Knockout Cell Lines are meticulously engineered cellular models in which the SPATA6 gene has been disrupted, thereby enabling comprehensive studies of the gene's function and its role in various biological processes. The SPATA6 gene is implicated in spermatogenesis, and its knockout facilitates the investigation of cellular mechanisms underlying male fertility and reproductive health. By using advanced CRISPR-Cas9 technology, these knockout cell lines can provide robust platforms for researchers seeking to explore gene function, signaling pathways, and the cellular events that lead to dysfunction in male reproductive systems.

The primary function of these knockout cell lines lies in their ability to mimic pathological conditions associated with the loss of SPATA6 activity. Through various assays, researchers can assess how the absence of this gene affects sperm development, cellular morphology, and even downstream signaling pathways. This model is essential for elucidating the genetic underpinnings of certain infertility cases and can yield insights into potential therapeutic targets for regenerative medicine or treatment of reproductive disorders.

The scientific importance of SPATA6 Gene Knockout Cell Lines is profound, particularly in reproductive biology and genetics. They are invaluable tools for pharmacological studies, facilitates drug discovery, and allow for the testing of innovative therapies aimed at restoring normal gene function. Clinically, they may pave the way for advancement in infertility treatments, contributing to improved outcomes for affected couples.

These cell lines offer distinct advantages over traditional models, such as primary sperm cultures or whole-animal models, by providing a controlled environment, reproducibility, and ease of manipulation. Additionally, researchers can conduct high-throughput experiments without ethical concerns associated with animal use.

In a landscape where precision and specificity are paramount, SPATA6 Gene Knockout Cell Lines represent an essential resource for both academic and pharmaceutical research. The expertise of our company in gene editing technologies ensures that each cell line is validated for optimal performance, allowing researchers to trust the integrity of their results and accelerate the discovery process. Embrace the potential of SPATA6 Gene Knockout Cell Lines to unlock the genetic mysteries of male fertility and enhance your research outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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