Gene: SP140L
Official Full Name: SP140 nuclear body protein likeprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22189 | SP140L Knockout cell line (HeLa) | Human | SP140L | 1:3~1:6 | Negative | Online Inquiry |
KO22190 | SP140L Knockout cell line (HCT 116) | Human | SP140L | 1:2~1:4 | Negative | Online Inquiry |
KO22191 | SP140L Knockout cell line (A549) | Human | SP140L | 1:3~1:4 | Negative | Online Inquiry |
SP140L Gene Knockout Cell Lines are a specialized biological tool designed for the study of gene function and regulation in mammalian systems. These cell lines are engineered to lack the SP140L gene, a key player in the regulation of immune responses and cellular signaling pathways. By utilizing CRISPR/Cas9 technology, the knockout of the SP140L gene allows researchers to investigate the specific roles of this gene in various biological processes, including immune modulation and gene expression dynamics.
The primary function of SP140L Gene Knockout Cell Lines is to serve as an experimental model to elucidate the role of SP140L in cellular mechanisms. By comparing these knockout lines to their wild-type counterparts, researchers can gain insights into the effects of SP140L absence on cell proliferation, apoptosis, and responses to external stimuli. This capability is crucial for understanding diseases that involve aberrant immune responses, such as autoimmune disorders and certain cancers.
In the realm of scientific research and clinical applications, these cell lines hold significant promise. They can be employed in drug discovery initiatives, where understanding the molecular interactions influenced by SP140L can lead to the identification of novel therapeutic targets. Furthermore, SP140L Gene Knockout Cell Lines can facilitate the exploration of genetic interactions and help researchers develop better models for human disease.
The unique selling points of SP140L Gene Knockout Cell Lines lie in their precision and reliability. Unlike traditional models, which may suffer from off-target effects and variability, these cell lines provide a consistent and reproducible platform for experimentation. Moreover, researchers can depend on these cell lines for high-throughput assays and mechanistic studies, saving time and resources in their investigative endeavors.
For researchers and clinicians, the value of SP140L Gene Knockout Cell Lines is clear: they offer an unparalleled opportunity to dissect complex biological systems and enhance our understanding of gene function in health and disease. Their applications span basic research to potential clinical implications, making them an invaluable asset.
Our company is dedicated to providing high-quality, meticulously validated biological products that empower scientific exploration and innovation. With expertise in molecular biology and cutting-edge techniques, we ensure that SP140L Gene Knockout Cell Lines meet the rigorous demands of the research community, advancing knowledge and discovery in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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