Gene: SNED1
Official Full Name: sushi, nidogen and EGF like domains 1provided by HGNC
Gene Summary: Predicted to enable Notch binding activity. Predicted to be involved in cell-matrix adhesion. Located in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28514 | SNED1 Knockout cell line (HCT 116) | Human | SNED1 | 1:2~1:4 | Negative | Online Inquiry |
KO28515 | SNED1 Knockout cell line (HEK293) | Human | SNED1 | 1:3~1:6 | Negative | Online Inquiry |
SNED1 Gene Knockout Cell Lines are engineered cellular models that have undergone precise genetic modifications to disrupt the expression of the SNED1 gene. This gene plays a crucial role in maintaining cellular functions, including cell adhesion, signaling pathways, and overall cellular morphology. By using these knockout cell lines, researchers can investigate the downstream effects of SNED1 loss, providing valuable insights into its role in various biological processes, such as development and disease progression.
The primary mechanism through which these knockout cell lines operate involves the targeted deletion of the SNED1 locus, achieved through advanced techniques, such as CRISPR-Cas9 or homologous recombination. The resulting cell lines lack functional SNED1 protein, allowing scientists to conduct comparative studies with wild-type cells. This makes it possible to elucidate the pathways and interactions affected by the absence of SNED1, facilitating research into cancer biology, neurodevelopmental disorders, and cell migration processes, thereby aiding in the translation of basic research into clinical applications.
The scientific importance of SNED1 Gene Knockout Cell Lines lies in their role as powerful tools for investigating gene function and validating drug targets. They provide a reliable platform for screening therapeutic compounds or identifying biomarkers associated with SNED1-related diseases. Moreover, their utilization can reveal potential compensatory mechanisms within cellular pathways, enhancing our understanding of genetic redundancy.
Compared to alternative models, such as whole organism or transient knockdown approaches, SNED1 Gene Knockout Cell Lines offer superior stability and reproducibility. They enable high-throughput applications, giving researchers the flexibility to perform extensive genetic and pharmacological studies without the confounding variability seen in other models.
For researchers and clinicians, the value of SNED1 Gene Knockout Cell Lines is underscored by their potential to accelerate discoveries in fundamental biology and translational medicine. By providing a chronic, stable genetic alteration, these cell lines serve as a foundational resource in the quest to develop innovative therapies and understand complex disease mechanisms.
Our company prides itself on their expertise in genetic engineering and cell line development, offering a robust portfolio of biological products that empower scientific exploration. With a commitment to providing high-quality, validated models, we support researchers in their pursuit of knowledge and advancements in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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