Gene: SMIM35
Official Full Name: small integral membrane protein 35provided by HGNC
Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13912 | SMIM35 Knockout cell line (HeLa) | Human | SMIM35 | 1:3~1:6 | Negative | Online Inquiry |
KO13913 | SMIM35 Knockout cell line (HCT 116) | Human | SMIM35 | 1:2~1:4 | Negative | Online Inquiry |
KO13914 | SMIM35 Knockout cell line (A549) | Human | SMIM35 | 1:3~1:4 | Negative | Online Inquiry |
SMIM35 Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the function of the SMIM35 gene, which encodes a small, membrane-associated protein implicated in various biological processes. These cell lines are created through a precise gene-editing technique, such as CRISPR-Cas9, leading to the functional disruption of the SMIM35 gene. By providing a definitive tool for researchers, these knockout cell lines enable the exploration of the gene's role in cellular mechanisms, disease modeling, and therapeutic target validation.
The primary function of the SMIM35 Gene Knockout Cell Lines is to facilitate the interrogation of cellular pathways affected by the loss of SMIM35. The absence of this gene allows scientists to observe resultant phenotypic changes, including alterations in cell proliferation, differentiation, and signaling pathways associated with apoptosis or immune response. In this manner, researchers can critically assess the biological impact of SMIM35's activity or inactivity, further illuminating its role in human health and disease.
The scientific importance of these cell lines cannot be overstated, as they offer versatile applications in basic research, drug discovery, and translational medicine. They serve as a crucial resource for studying conditions where SMIM35 may play a pivotal role, such as in cancer, cardiovascular diseases, or autoimmune disorders. Importantly, such models can expedite preclinical evaluations of potential therapeutic compounds aimed at modulating SMIM35-related pathways.
Unlike conventional cell lines that may not accurately reflect the absence of the SMIM35 gene, our knockout models provide a reliable and efficient system to obtain reproducible results. Additionally, these cell lines are rigorously validated for genotype and phenotype, ensuring that researchers receive consistent and high-quality data.
For researchers and clinicians focused on elucidating molecular pathways and therapeutic interventions, the SMIM35 Gene Knockout Cell Lines are invaluable. They streamline experimental design, offer clear insights into gene function, and pave the way for advancements in understanding complex diseases.
At [Your Company Name], we pride ourselves on our expertise in developing innovative biological tools. We are dedicated to providing products that empower life sciences research and foster scientific discovery, ensuring our clients have access to the highest quality resources for their investigational needs.
Please note that all services are for research use only. Not intended for any clinical use.
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