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SLK Knockout Cell Lines

Gene: SLK

Official Full Name: STE20 like kinaseprovided by HGNC

Gene Summary: Enables protein homodimerization activity and protein serine/threonine kinase activity. Involved in several processes, including cytoplasmic microtubule organization; protein autophosphorylation; and regulation of focal adhesion assembly. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07309 SLK Knockout cell line (HeLa) Human SLK 1:3~1:6 Negative Online Inquiry
KO07310 SLK Knockout cell line (HCT 116) Human SLK 1:2~1:4 Negative Online Inquiry
KO07311 SLK Knockout cell line (HEK293) Human SLK 1:3~1:6 Negative Online Inquiry
KO07312 SLK Knockout cell line (A549) Human SLK 1:3~1:4 Negative Online Inquiry

Background

SLK Gene Knockout Cell Lines are a specialized suite of cellular models engineered to enable precise gene function analysis and elucidation of signaling pathways associated with SLK (serine/threonine kinase). These cell lines utilize advanced CRISPR-Cas9 technology to create targeted deletions of the SLK gene, allowing for the systematic investigation of its role in cell proliferation, differentiation, and response to various stimuli. By inactivating the SLK gene, researchers can effectively study the downstream effects on cellular signaling networks and explore pathways involved in cancer progression, metabolic regulation, and other critical biological processes.

The primary mechanism of these cell lines hinges on the ability of CRISPR-Cas9 to induce double-strand breaks in DNA, triggering the cell's repair mechanisms to create knockout mutations. This ensures that the model closely mimics pathological conditions where SLK expression may be altered or dysregulated. The SLK Gene Knockout Cell Lines are particularly valuable in both research and clinical settings, where understanding the precise contributions of SLK to cellular dynamics is essential for developing targeted therapies, especially in oncology.

When compared to other knockout technologies, our SLK Gene Knockout Cell Lines stand out due to their high efficiency and specificity. Unlike traditional methods that may lead to off-target effects and unpredictable results, our products provide reliable and reproducible models that are vetted for quality assurance. This feature significantly accelerates research timelines while minimizing experimental variability.

For researchers and clinicians aiming to advance the understanding of SLK-related biological mechanisms, the SLK Gene Knockout Cell Lines represent an indispensable tool. Their capacity to facilitate high-throughput screening and functional assays promises to uncover insights that could lead to novel therapeutic strategies and improved clinical outcomes.

With a strong commitment to innovation and scientific excellence, our company specializes in the development of high-quality biological products that empower researchers to explore complex biological questions with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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