Gene: SLITRK6
Official Full Name: SLIT and NTRK like family member 6provided by HGNC
Gene Summary: This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25112 | SLITRK6 Knockout cell line (A549) | Human | SLITRK6 | 1:3~1:4 | Negative | Online Inquiry |
SLITRK6 Gene Knockout Cell Lines are specially engineered cellular models designed to study the functional role of the SLITRK6 gene, which is implicated in various neurological and developmental processes. By using CRISPR-Cas9 gene editing technology, these cell lines have had the SLITRK6 gene disrupted, allowing researchers to investigate its contributions to cellular signaling and synaptic function without the interference of its normal expression.
The primary function of the SLITRK6 protein is its involvement in neuronal development and the modulation of synaptic plasticity, which plays a critical role in learning and memory. By utilizing these knockout cell lines, researchers can explore the molecular pathways affected by the absence of SLITRK6, facilitating a deeper understanding of its role in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia. This understanding is crucial for developing targeted therapies and interventions.
In the realm of scientific research, SLITRK6 Gene Knockout Cell Lines offer invaluable tools for high-throughput screening and drug discovery processes. They provide a platform for evaluating the effects of candidate compounds on neuronal physiology and pathology in a controlled setting. Compared to traditional wild-type cell lines, these knockout models specifically highlight the functional deficits caused by the absence of SLITRK6, providing more relevant data for neurobiological studies.
Researchers and clinicians can benefit significantly from the specificity and precision of the SLITRK6 knockout models. They have the potential to elucidate complex genetic interactions and their repercussions on neurological conditions, paving the way for innovative therapeutic strategies. The unique selling point of these cell lines lies in their ability to bridge fundamental research and clinical applications, meriting attention from laboratories focused on neurobiology and therapeutic development.
Our company prides itself on delivering cutting-edge biological products backed by a team of experts dedicated to advancing scientific discovery. With our commitment to quality and innovation, we provide researchers with the tools necessary to push the boundaries of knowledge in the field of genetics and neurobiology.
Please note that all services are for research use only. Not intended for any clinical use.
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