Gene: SLC9A6
Official Full Name: solute carrier family 9 member A6provided by HGNC
Gene Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00282 | SLC9A6 Knockout cell line (HeLa) | Human | SLC9A6 | 1:3~1:6 | Negative | Online Inquiry |
KO31828 | SLC9A6 Knockout cell line (HCT 116) | Human | SLC9A6 | 1:2~1:4 | Negative | Online Inquiry |
KO31829 | SLC9A6 Knockout cell line (HEK293) | Human | SLC9A6 | 1:3~1:6 | Negative | Online Inquiry |
KO31830 | SLC9A6 Knockout cell line (A549) | Human | SLC9A6 | 1:3~1:4 | Negative | Online Inquiry |
SLC9A6 Gene Knockout Cell Lines are sophisticated biological tools designed to facilitate the study of the SLC9A6 gene’s role in cellular processes. The SLC9A6 gene encodes the sodium/hydrogen exchanger 6, a critical protein involved in maintaining ionic balance and intracellular pH; its dysfunction is associated with various neurological disorders. By utilizing CRISPR-Cas9 gene-editing technology, these knockout cell lines exhibit a complete disruption of the SLC9A6 gene, allowing researchers to investigate the downstream effects of its absence in a controlled environment.
The primary function of these cell lines is to simulate the pathological conditions linked to SLC9A6 gene mutations, enabling comprehensive studies on cellular responses, signaling pathways, and molecular interactions. Researchers can analyze phenotypic changes, scrutinize regulatory mechanisms, and better understand the implications of ion imbalance at the cellular level. These cell lines are particularly valuable in research that aims to elucidate the pathogenesis of diseases such as intellectual disability and other neurodevelopmental disorders.
Compared to traditional models, SLC9A6 Gene Knockout Cell Lines offer unique advantages, including precise gene editing, reproducibility, and the ability to manipulate additional variables via transfection. These features significantly enhance experimental accuracy, driving more reliable outcomes. Furthermore, the convenience of having established cell lines expedites research timelines, allowing scientists to focus on data generation and analysis rather than initial model development.
For researchers and clinicians exploring the field of genetic disorders, SLC9A6 Gene Knockout Cell Lines represent an invaluable resource, enabling them to uncover critical insights that may pave the way for innovative therapeutic strategies. Our company prides itself on delivering high-quality, robust biological products that empower scientific discovery, backed by extensive expertise in gene editing technologies and their applications. With this offering, we aim to support the advancement of research and improve clinical outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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