Gene: SLC8B1
Official Full Name: solute carrier family 8 member B1provided by HGNC
Gene Summary: SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00910 | SLC8B1 Knockout cell line(HCT 116) | Human | SLC8B1 | 1:2~1:4 | Negative | Online Inquiry |
KO14099 | SLC8B1 Knockout cell line (HeLa) | Human | SLC8B1 | 1:3~1:6 | Negative | Online Inquiry |
KO14100 | SLC8B1 Knockout cell line (HEK293) | Human | SLC8B1 | 1:3~1:6 | Negative | Online Inquiry |
KO14101 | SLC8B1 Knockout cell line (A549) | Human | SLC8B1 | 1:3~1:4 | Negative | Online Inquiry |
SLC8B1 Gene Knockout Cell Lines are meticulously engineered cellular models that have had the SLC8B1 gene ablated, allowing researchers to investigate the physiological and pathological roles of this gene in various biological processes. The SLC8B1 gene encodes the sodium/calcium exchanger, a critical protein involved in the regulation of intracellular calcium levels. By knocking out this gene, researchers can examine the downstream effects on cellular calcium homeostasis, muscle contraction, neurotransmitter release, and other calcium-signaling pathways.
The primary function of SLC8B1 Gene Knockout Cell Lines is to enable the study of homeostatic mechanisms that involve calcium ions. The absence of the SLC8B1 protein allows for precise assessments of calcium dynamics within the cell, making these lines invaluable for pharmacological studies that aim to identify compounds capable of modulating calcium signaling. Furthermore, these cell lines can serve as models for diseases where calcium dysregulation is prevalent, such as cardiac arrhythmias or neurodegenerative disorders.
The scientific importance of these cell lines lies in their capacity to facilitate research in both basic biology and drug discovery phases. They offer a unique opportunity for scientists to determine the role of SLC8B1 in various conditions, making them critical tools for translational research aimed at developing novel treatments.
What sets SLC8B1 Gene Knockout Cell Lines apart from alternative products is their high specificity and reliability. Built upon robust CRISPR/Cas9 gene-editing technology, these knockout lines exhibit consistent and reproducible results in various assays. This level of precision not only enhances experimental accuracy but also reduces the variability commonly associated with other methods.
For researchers and clinicians, SLC8B1 Gene Knockout Cell Lines present an exceptional opportunity to deepen their understanding of calcium-related disorders and improve the development of therapeutics aimed at such conditions. By utilizing these tailored models, researchers can expedite their studies while potentially leading to impactful discoveries.
At [Your Company Name], we are committed to delivering high-quality biological products backed by extensive expertise in genetic engineering and cellular research. Our SLC8B1 Gene Knockout Cell Lines are a testament to our dedication to innovation and excellence in the field of life sciences, providing tools that empower researchers to make significant scientific advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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