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SLC38A7 Knockout Cell Lines

Gene: SLC38A7

Official Full Name: solute carrier family 38 member 7provided by HGNC

Gene Summary: Enables L-asparagine:sodium symporter activity and L-glutamine:sodium symporter activity. Involved in asparagine transport and glutamine transport. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00356 SLC38A7 Knockout cell line (HeLa) Human SLC38A7 1:3~1:6 Negative Online Inquiry
KO20126 SLC38A7 Knockout cell line (HCT 116) Human SLC38A7 1:2~1:4 Negative Online Inquiry
KO20127 SLC38A7 Knockout cell line (HEK293) Human SLC38A7 1:3~1:6 Negative Online Inquiry
KO20128 SLC38A7 Knockout cell line (A549) Human SLC38A7 1:3~1:4 Negative Online Inquiry

Background

SLC38A7 Gene Knockout Cell Lines are genetically engineered cell lines in which the SLC38A7 gene has been systematically disrupted through CRISPR-Cas9 technology. This innovative approach facilitates the study of the gene's physiological functions and its roles in various metabolic processes, particularly in the context of amino acid transport and cellular signaling pathways. By creating a loss-of-function model, researchers can better understand the consequences of SLC38A7 deficiency and its implications in pathological conditions.

The primary function of these knockout cell lines lies in their ability to help elucidate the mechanistic pathways regulated by SLC38A7. This gene is known to be involved in maintaining cellular homeostasis by regulating nutrient transport and influencing overall cell metabolism. Using these knockout lines, scientists can investigate how the absence of SLC38A7 affects cellular responses to nutrients, stress, and environment—a critical insight for metabolic research and drug development.

The scientific significance of SLC38A7 Gene Knockout Cell Lines extends to both academic research and clinical applications. By providing a model system to probe amino acid metabolism disorders, these cell lines are invaluable in drug screening, biomarker discovery, and elucidation of disease mechanisms such as cancer, neurodegenerative disorders, and metabolic syndrome. As a result, they serve as critical tools for both preclinical and translational studies.

Compared to alternative models such as wild-type cell lines or knockdown systems, the complete knockout offers a clearer understanding of SLC38A7 function, eliminating any residual gene activity that could confound results. This precision makes SLC38A7 knockout cell lines particularly advantageous for tailoring experiments focused on gene-specific effects.

For researchers, clinicians, and biopharmaceutical companies, the acquisition of SLC38A7 Gene Knockout Cell Lines represents a step towards advancing our understanding of complex biological systems and developing targeted therapeutic strategies. With years of expertise in genetic engineering and a commitment to supporting innovative biological research, our company stands at the forefront of delivering high-quality models that empower scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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