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SLC26A6 Knockout Cell Lines

Gene: SLC26A6

Official Full Name: solute carrier family 26 member 6provided by HGNC

Gene Summary: This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14049 SLC26A6 Knockout cell line (HeLa) Human SLC26A6 1:3~1:6 Negative Online Inquiry
KO14050 SLC26A6 Knockout cell line (HCT 116) Human SLC26A6 1:2~1:4 Negative Online Inquiry
KO14051 SLC26A6 Knockout cell line (HEK293) Human SLC26A6 1:3~1:6 Negative Online Inquiry
KO14052 SLC26A6 Knockout cell line (A549) Human SLC26A6 1:3~1:4 Negative Online Inquiry

Background

SLC26A6 Gene Knockout Cell Lines are genetically engineered cell lines that feature the targeted deletion of the SLC26A6 gene, which encodes for an important member of the solute carrier (SLC) family involved in the transport of anions and organic compounds across cell membranes. These knockout models are crucial for researchers aiming to elucidate the physiological and pathological roles of SLC26A6 in various biological processes, particularly in systems related to ion transport, acid-base balance, and cellular signaling.

The key function of these cell lines is to provide a controlled environment to study the functional consequences of SLC26A6 deficiency. By eliminating this gene, researchers can investigate its influence on cellular behaviors such as ion transport, pH regulation, and its overall impact on cell physiology. Mechanistically, these studies often reveal changes in cellular homeostasis and provide insights into related disorders, including gastrointestinal and kidney functions, paving the way for potential therapeutic interventions.

The scientific importance of SLC26A6 Gene Knockout Cell Lines is underscored by their application in both basic research and clinical settings. They support the investigation of disease mechanisms linked to ion transport deficits and can facilitate drug discovery by identifying new therapeutic targets. Furthermore, by utilizing these knockout models, scientists can explore compensatory mechanisms that arise in the absence of SLC26A6.

One of the unique advantages of our SLC26A6 Gene Knockout Cell Lines lies in their precision and reproducibility compared to other models. Traditional methods such as chemical inhibitors or siRNA knockdown may lead to off-target effects or transient modifications, whereas our knockout cell lines offer a stable, long-term study of SLC26A6's role without these limitations. This specificity is invaluable for researchers seeking reliable data in cell signaling pathways or pharmacological testing.

The value of SLC26A6 Gene Knockout Cell Lines to researchers and clinicians is evident in their potential to accelerate discoveries in ion transport biology and related therapeutic strategies. They enable more robust experimental designs and enhance the understanding of complex biological systems, ultimately contributing to improved patient outcomes.

Our company specializes in the development of high-quality genetic models tailored to support advanced research needs. With a strong foundation in molecular biology and a commitment to scientific excellence, we empower our customers with tools that enhance their research capabilities and drive impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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