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SLC25A18 Knockout Cell Lines

Gene: SLC25A18

Official Full Name: solute carrier family 25 member 18provided by HGNC

Gene Summary: Enables amino acid:proton symporter activity. Involved in L-glutamate transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25385 SLC25A18 Knockout cell line (HEK293) Human SLC25A18 1:3~1:6 Negative Online Inquiry

Background

SLC25A18 Gene Knockout Cell Lines are specialized tools utilized in biological research to investigate the functional implications of the SLC25A18 gene, which encodes a mitochondrial transporter involved in regulating cellular metabolism and energy production. By precisely deleting or "knocking out" this gene, researchers can examine the consequences on cellular physiology and metabolic pathways, providing insights into mitochondrial function and its role in various diseases.

These knockout cell lines are engineered through CRISPR/Cas9 technology, a powerful and precise gene-editing tool known for its efficiency and specificity. This methodology allows for the targeted disruption of the SLC25A18 gene, facilitating the evaluation of related biochemical changes and phenotypic characteristics. As a result, researchers can elucidate the gene's therapeutic targets, regulatory networks, and its contributions to metabolic disorders, neurodegeneration, and cancer.

The scientific importance of SLC25A18 knockout cell lines lies in their ability to serve as model systems that mimic pathophysiological conditions. In clinical settings, understanding the role of mitochondrial transporters is critical, as dysregulation of energy metabolism is implicated in a range of diseases. Therefore, these cell lines can assist in screening potential drug candidates or developing gene therapies.

Compared to other experimental models, SLC25A18 knockout cell lines offer a direct approach to assess gene function and interaction within a controlled environment, providing a more accurate representation of human cellular responses. Their ease of use, combined with versatile applications across multiple research domains, differentiates them from traditional cell culture systems.

For researchers and clinicians focused on mitochondrial biology, metabolic regulation, and therapeutic innovation, SLC25A18 Gene Knockout Cell Lines are invaluable resources. They not only enhance experimental accuracy but also accelerate the discovery process in understanding mitochondrial diseases. Our company is committed to advancing biological research through the provision of high-quality genetic models, ensuring researchers have the tools they need to uncover the complexities of cellular function.

Please note that all services are for research use only. Not intended for any clinical use.

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