Gene: SLC25A17
Official Full Name: solute carrier family 25 member 17provided by HGNC
Gene Summary: This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31831 | SLC25A17 Knockout cell line (HeLa) | Human | SLC25A17 | 1:3~1:6 | Negative | Online Inquiry |
KO31832 | SLC25A17 Knockout cell line (HCT 116) | Human | SLC25A17 | 1:2~1:4 | Negative | Online Inquiry |
KO31833 | SLC25A17 Knockout cell line (HEK293) | Human | SLC25A17 | 1:3~1:6 | Negative | Online Inquiry |
KO31834 | SLC25A17 Knockout cell line (A549) | Human | SLC25A17 | 1:3~1:4 | Negative | Online Inquiry |
SLC25A17 Gene Knockout Cell Lines are genetically engineered cell line models specifically designed to study the SLC25A17 gene, which encodes a mitochondrial carrier protein involved in the transport of various metabolites, including coenzymes and nucleotide precursors. By creating knockout models, researchers can effectively elucidate the gene's physiological roles and its implications in metabolic diseases and cellular energy homeostasis.
The primary function of SLC25A17 knockout cell lines is to investigate the downstream effects of the absence of this essential transporter. This is achieved through the disruption of the gene's expression, leading to altered mitochondrial function and distinct metabolic profiles. Such cell lines enable researchers to conduct targeted experiments to understand the biochemical pathways regulated by SLC25A17 and to evaluate how its dysfunction may contribute to pathological conditions.
The scientific importance of SLC25A17 knockout cell lines lies in their application in both research and clinical settings. They serve as invaluable tools for studying mitochondrial dysfunction, exploring novel therapeutic strategies for diseases linked to energy metabolism, and identifying biomarker candidates for early diagnosis or treatment monitoring. Furthermore, these models are essential for drug discovery processes, providing insights into the interaction between potential therapeutic agents and mitochondrial carriers.
One distinct advantage of using SLC25A17 knockout cell lines over alternative models is their specificity and ability to closely mimic human physiology. Other generic knockout models may fail to replicate the nuanced roles of specific genes; however, these specialized lines facilitate more accurate, high-throughput screening and mechanistic studies.
In conclusion, SLC25A17 Gene Knockout Cell Lines represent a critical advancement for researchers and clinicians focused on metabolic diseases and mitochondrial function. With our company’s extensive expertise in genetic engineering and cell line development, we are committed to providing high-quality, reliable biological products that drive innovation in scientific research.
Please note that all services are for research use only. Not intended for any clinical use.
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