Gene: SKIC2
Official Full Name: SKI2 subunit of superkiller complexprovided by HGNC
Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14124 | SKIC2 Knockout cell line (HeLa) | Human | SKIC2 | 1:3~1:6 | Negative | Online Inquiry |
KO14125 | SKIC2 Knockout cell line (HCT 116) | Human | SKIC2 | 1:2~1:4 | Negative | Online Inquiry |
KO14126 | SKIC2 Knockout cell line (HEK293) | Human | SKIC2 | 1:3~1:6 | Negative | Online Inquiry |
KO14127 | SKIC2 Knockout cell line (A549) | Human | SKIC2 | 1:3~1:4 | Negative | Online Inquiry |
SKIC2 Gene Knockout Cell Lines are a sophisticated tool designed for researchers aiming to investigate the biological functions of the SKIC2 gene and its implications in various cellular processes. These cell lines have been meticulously engineered through CRISPR/Cas9 technology to create a complete loss of function for the SKIC2 gene, allowing for precise analysis of its role in signal transduction, cell metabolism, and disease pathways.
The primary functions of the SKIC2 Gene Knockout Cell Lines center around enabling the exploration of the gene’s regulatory roles and its interactions within molecular networks. By providing an accurate representation of cellular responses in the absence of SKIC2, researchers can unravel the gene's contributions to critical processes such as cell proliferation, differentiation, and apoptosis. This insight is essential for advancing knowledge in fields such as cancer biology, metabolic disorders, and regenerative medicine.
In both research and clinical settings, these cell lines hold significant importance, serving as a valuable resource for drug discovery, target validation, and functional genomics studies. Researchers can leverage the SKIC2 knockout model to assess the impact of potential therapeutic agents on cell behavior or to elucidate the pathogenic mechanisms underlying various diseases associated with dysregulated SKIC2 signaling.
What sets our SKIC2 Gene Knockout Cell Lines apart from alternative products on the market is the unparalleled reliability and reproducibility offered by our proprietary engineering methods. Each cell line undergoes rigorous quality control, ensuring consistent performance and genomic integrity. Additionally, our commitment to user-friendly resources facilitates streamlined experimental design, enabling researchers to focus their efforts on generating impactful data rather than troubleshooting model inconsistencies.
For researchers, clinicians, and pharmacologists alike, the SKIC2 Gene Knockout Cell Lines represent a transformative tool that enhances experimental rigour and accelerates discoveries. As a leader in the field of biological products, our company vows to provide state-of-the-art solutions backed by solid scientific expertise, ensuring the highest standards in research innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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