Gene: SH3RF2
Official Full Name: SH3 domain containing ring finger 2provided by HGNC
Gene Summary: Enables protein phosphatase 1 binding activity and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of JNK cascade; protein autoubiquitination; and regulation of protein metabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21491 | SH3RF2 Knockout cell line (HeLa) | Human | SH3RF2 | 1:3~1:6 | Negative | Online Inquiry |
KO21492 | SH3RF2 Knockout cell line (HCT 116) | Human | SH3RF2 | 1:2~1:4 | Negative | Online Inquiry |
KO21493 | SH3RF2 Knockout cell line (A549) | Human | SH3RF2 | 1:3~1:4 | Negative | Online Inquiry |
SH3RF2 Gene Knockout Cell Lines are genetically engineered cell models that have been specifically designed to lack the function of the SH3RF2 gene, known to play significant roles in cellular signaling and membrane trafficking. By utilizing CRISPR-Cas9 technology for precise gene editing, these cell lines provide researchers with a powerful tool for examining the downstream effects of SH3RF2 depletion.
The primary function of SH3RF2 involves the regulation of various signaling pathways, contributing to cellular responses to external stimuli. By removing this gene, scientists can investigate its role in processes such as cell proliferation, differentiation, and apoptosis, thereby elucidating the molecular pathways affected by its absence. Mechanistically, knockout cell lines serve as important platforms for studies on the regulatory roles the SH3RF2 protein exerts, as the loss of such proteins can lead to pathological states.
The scientific importance of SH3RF2 Gene Knockout Cell Lines is underscored by their applications in both basic and applied research areas, such as cancer biology, neurobiology, and developmental studies. Understanding how the absence of SH3RF2 alters cellular behavior is crucial for identifying potential therapeutic targets and strategies, especially in diseases where this gene is implicated.
One of the significant advantages of using SH3RF2 Gene Knockout Cell Lines is their precise genetic alteration, which offers a clear advantage over transient knockdown methods that may produce variable results. Additionally, these cell lines can facilitate high-throughput screening for potential drug compounds designed to modulate the pathways affected by this gene.
For researchers, clinicians, and biotechnology professionals, SH3RF2 Gene Knockout Cell Lines represent an invaluable resource that accelerates discovery and enhances the understanding of complex biological systems. Their robustness and reliability provide a solid foundation for cutting-edge research that could lead to significant breakthroughs in therapeutic development. As a company dedicated to advancing scientific knowledge, we pride ourselves on offering high-quality biological products like SH3RF2 Gene Knockout Cell Lines, reflecting our commitment to excellence and innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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