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SH3D21 Knockout Cell Lines

Gene: SH3D21

Official Full Name: SH3 domain containing 21provided by HGNC

Gene Summary: Predicted to be involved in actin filament organization and cell migration. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14169 SH3D21 Knockout cell line (HeLa) Human SH3D21 1:3~1:6 Negative Online Inquiry
KO14170 SH3D21 Knockout cell line (HCT 116) Human SH3D21 1:2~1:4 Negative Online Inquiry
KO14171 SH3D21 Knockout cell line (HEK293) Human SH3D21 1:3~1:6 Negative Online Inquiry
KO14172 SH3D21 Knockout cell line (A549) Human SH3D21 1:3~1:4 Negative Online Inquiry

Background

SH3D21 Gene Knockout Cell Lines are specialized cellular models created through the CRISPR-Cas9 gene-editing technology, designed specifically to study the SH3D21 gene’s role in various biological processes. These cell lines facilitate the targeted disruption of the SH3D21 locus, enabling researchers to investigate the gene's functions, interactions, and contributions to cellular pathways, particularly in fields like cancer biology and developmental studies.

The primary mechanism of action involves the introduction of double-strand breaks at the SH3D21 locus, followed by the cell's natural repair processes, which result in gene knockout through non-homologous end joining. This approach allows for precise genetic modifications that can disrupt normal gene function and lead to observable phenotypic changes. As a result, researchers can elucidate the physiological relevance of SH3D21 in normal and disease states, thereby advancing our understanding of its potential as a therapeutic target.

From a scientific standpoint, SH3D21 Gene Knockout Cell Lines are invaluable tools for basic research and translational studies. The ability to manipulate a specific gene enables researchers to dissect molecular mechanisms and investigate gene-gene interactions, making it possible to explore the implications of SH3D21 in various disease processes. The use of these cell lines in drug discovery and development is particularly noteworthy, as they permit the screening of therapeutic compounds aimed at modulating SH3D21-related pathways.

Compared to alternative models, such as traditional knockout mice or lentiviral systems, SH3D21 Gene Knockout Cell Lines offer rapid generation times and greater consistency in cellular responses. These cell lines are already adapted for high-throughput screening, making them an attractive choice for researchers aiming to accelerate their experimental timelines and reduce resource expenditure.

For researchers and clinicians focused on genetic and cellular biology, SH3D21 Gene Knockout Cell Lines represent a significant advancement in the toolkit available for gene function studies. Their detailed characterization and application to real-world biological questions underscore their unique position in scientific inquiry. Our company specializes in producing high-quality biological products, ensuring that our customers have access to reliable and innovative tools to advance their research. With expertise rooted in rigorous scientific methodologies, we are committed to supporting the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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