Gene: SERPINB5
Official Full Name: serpin family B member 5provided by HGNC
Gene Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Located in cytoplasm. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06825 | SERPINB5 Knockout cell line (HeLa) | Human | SERPINB5 | 1:3~1:6 | Negative | Online Inquiry |
KO06826 | SERPINB5 Knockout cell line (HCT 116) | Human | SERPINB5 | 1:2~1:4 | Negative | Online Inquiry |
SERPINB5 Gene Knockout Cell Lines are engineered cellular models that feature deliberate inactivation of the SERPINB5 gene, which encodes a serpin (serine protease inhibitor) involved in various biological processes, such as cellular regulation and tumor progression. These knockout cell lines serve as powerful tools in biomedicine by enabling researchers to elucidate the role of SERPINB5 in various pathophysiological states, especially its implications in cancer biology.
The primary function of SERPINB5 is to regulate serine proteases, which can influence processes such as apoptosis, inflammation, and tissue remodeling. By knocking out the SERPINB5 gene, scientists can study the altered signaling pathways and biological functions resulting from the absence of this inhibitor. The mechanisms of action for the resulting cell lines provide insights into tumor microenvironments, metastasis, and cellular resilience against proteolytic activity.
In both research and clinical settings, SERPINB5 Gene Knockout Cell Lines are essential for advancing our understanding of cancer development and progression, enabling the identification of new therapeutic targets. Applications include drug discovery, where researchers can screen for compounds that harness or counteract the effects of disrupted SERPINB5 activity. Moreover, these cell lines can aid in understanding tumor behavior, leading to improved diagnostics and treatment plans.
What sets our SERPINB5 Gene Knockout Cell Lines apart from conventional approaches is their precision and reliability. These lines are developed using advanced genetic engineering techniques, ensuring consistent knockout efficiency and reproducibility across experiments. Compared to wild-type cell lines, the knockout variants allow for clearer interpretations of experimental outcomes, supporting more robust conclusions.
Ultimately, the SERPINB5 Gene Knockout Cell Lines provide invaluable resources for researchers and clinicians aiming to unravel complex cellular mechanisms and improve therapeutic strategies. Our company excels in providing high-quality, well-characterized biological products that aid in pivotal research and contribute to the advancement of health science, ensuring that your studies are built on solid, reliable foundations.
Please note that all services are for research use only. Not intended for any clinical use.
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