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SDC2 Knockout Cell Lines

Gene: SDC2

Official Full Name: syndecan 2provided by HGNC

Gene Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04445 SDC2 Knockout cell line (HeLa) Human SDC2 1:3~1:6 Negative Online Inquiry
KO04446 SDC2 Knockout cell line (HEK293) Human SDC2 1:3~1:6 Negative Online Inquiry

Background

SDC2 Gene Knockout Cell Lines are genetically engineered cell lines that have had the SDC2 gene, associated with cellular signaling and adhesion processes, specifically disrupted or "knocked out." This precise genetic alteration allows researchers to study the role of SDC2 in various biological contexts, including its influence on cellular migration, proliferation, and differentiation.

The primary function of these knockout cell lines is to serve as a valuable tool for investigating the molecular mechanisms underlying diseases such as cancer, where SDC2 is believed to play a critical role in tumor progression and metastasis. By analyzing the behavior of these cells in vitro, scientists can gain insights into the pathways affected by the absence of SDC2, ultimately leading to a better understanding of the gene's contributions to pathology.

The scientific importance of SDC2 Gene Knockout Cell Lines extends to multiple domains of research and clinical applications. They can be utilized in drug discovery to identify potential therapeutic targets or evaluate the efficacy of novel treatments. Furthermore, these cell lines can serve as a model system for studying genetic interactions within signaling networks, providing comprehensive understanding that can translate into clinical advancements.

What sets SDC2 Gene Knockout Cell Lines apart from other models is their specificity and reproducibility. By offering a precise knockout of the SDC2 gene, these cell lines enable consistent and accurate investigation of the gene's functions, an advantage that is crucial when making comparisons to wild-type behaviors. Compared to traditional gene silencing techniques, the knockout approach mitigates off-target effects, ensuring more reliable experimental outcomes.

These cell lines are immensely valuable to researchers and clinicians aiming to uncover the complexities of gene function in health and disease. With the ability to manipulate gene expression in a controlled manner, they present a versatile resource for advancing biological knowledge and therapeutic strategies.

Our company specializes in providing high-quality genetic tools and models, supporting the scientific community with innovative products that facilitate groundbreaking research. With a commitment to excellence, we are dedicated to empowering researchers with reliable resources, ensuring that advancements in biomedicine can be achieved with confidence and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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