Gene: SCUBE1
Official Full Name: signal peptide, CUB domain and EGF like domain containing 1provided by HGNC
Gene Summary: This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26066 | SCUBE1 Knockout cell line (HEK293) | Human | SCUBE1 | 1:3~1:6 | Negative | Online Inquiry |
SCUBE1 Gene Knockout Cell Lines are sophisticated biological research tools designed to investigate the functional roles of the SCUBE1 gene in various physiological and pathological processes. These cell lines have been genetically engineered to silence the expression of the SCUBE1 gene, allowing researchers to study the consequences of its absence in cellular behavior, signaling pathways, and disease models. The mechanism behind their effectiveness lies in the targeted gene editing techniques, such as CRISPR-Cas9, which result in precise and stable gene knockout that facilitates the exploration of gene function in controlled experimental settings.
The scientific importance of SCUBE1 Gene Knockout Cell Lines is profound, particularly in cancer research, developmental biology, and regenerative medicine. SCUBE1 has been implicated in several key biological processes, including cell adhesion, migration, and differentiation. By utilizing these knockout lines, researchers can elucidate SCUBE1's role in tumor progression, tissue regeneration, and inflammatory responses, providing insight into novel therapeutic strategies. Furthermore, these cell lines are essential for drug discovery and testing, offering a reliable platform for evaluating potential pharmacological interventions.
Compared to traditional methods of gene manipulation, such as siRNA or shRNA approaches, SCUBE1 Gene Knockout Cell Lines offer several distinct advantages. The knockout approach provides a more definitive and permanent alteration of gene expression, which is crucial for long-term studies. Additionally, these cell lines reduce off-target effects often seen with transient knockdown strategies, enabling clearer interpretations of experimental results.
For researchers and clinicians, SCUBE1 Gene Knockout Cell Lines represent a valuable resource that accelerates the pace of discovery and enhances the reliability of experimental outcomes. By providing robust and reproducible models, these cell lines empower the scientific community to advance their understanding of SCUBE1's contributions to biology and disease.
Our company specializes in delivering high-quality genetically modified cell lines, leveraging cutting-edge techniques and a commitment to excellence in biological research. By choosing our SCUBE1 Gene Knockout Cell Lines, you are ensuring access to reliable tools that can significantly elevate your research capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
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