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SBK3 Knockout Cell Lines

Gene: SBK3

Official Full Name: SH3 domain binding kinase family member 3provided by HGNC

Gene Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromatin remodeling. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14339 SBK3 Knockout cell line (A549) Human SBK3 1:3~1:4 Negative Online Inquiry

Background

SBK3 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the SBK3 gene, known for its critical role in various cellular processes, including proliferation, differentiation, and response to stress conditions. Utilizing the CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the SBK3 gene, enabling researchers to investigate the gene's function or its involvement in pathological conditions without the confounding influence of its expression.

These knockout cell lines function by providing a controlled environment in which the absence of the SBK3 gene can elucidate its biological pathways and interactions. This absence allows for the assessment of phenotypic changes, gene expression patterns, and potential signaling cascades that are otherwise masked in wild-type cells. Consequently, the SBK3 Gene Knockout Cell Lines serve as pivotal tools in molecular biology and cancer research, where understanding gene involvement in tumorigenesis is essential for the development of targeted therapies.

The scientific importance of SBK3 knockout models cannot be overstated. They have significant applications in drug discovery, therapeutic interventions, and basic research, offering insights into the mechanistic roles of SBK3 in diseases such as cancer and neurodegeneration. Moreover, these cell lines present a reliable platform for high-throughput screening assays that require accurate gene function assessment in the absence of interference from SBK3 activity.

Compared to traditional gene knockout methods, SBK3 Gene Knockout Cell Lines stand out due to their enhanced precision, reproducibility, and the speed with which researchers can achieve functional validation. These cell lines minimize the risk of off-target effects that are often associated with previous knockout technologies and come ready to use, which significantly accelerates experimental timelines.

For researchers, clinicians, and biotech companies, investing in SBK3 Gene Knockout Cell Lines means gaining access to a robust resource designed for pioneering exploration in genetic research. Utilizing our expertise in cell line development and gene editing, we pride ourselves on delivering high-quality biological products that empower scientific discovery, enhance research outcomes, and ultimately contribute to advancements in therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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