Gene: RTN1
Official Full Name: reticulon 1provided by HGNC
Gene Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35560 | RTN1 Knockout cell line (HEK293) | Human | RTN1 | 1:3~1:6 | Negative | Online Inquiry |
RTN1 Gene Knockout Cell Lines represent a cutting-edge advancement in genetic research, designed specifically to study the function of the reticulon 1 (RTN1) gene. These cell lines have been engineered using CRISPR-Cas9 technology to achieve a complete knockout of the RTN1 gene, allowing researchers to investigate the gene's implications in various cellular processes and diseases, including neurodegenerative disorders and cancer.
The primary function of these knockout cell lines is to facilitate the elucidation of RTN1's role in maintaining endoplasmic reticulum (ER) structure and function. By observing the phenotypic changes in these cells, researchers can gain valuable insights into how RTN1 contributes to protein folding, lipid metabolism, and cellular stress responses. The knockout model allows for a clearer understanding of the mechanistic pathways influenced by RTN1, providing a platform for identifying potential therapeutic targets.
The scientific importance of RTN1 Gene Knockout Cell Lines extends to both research and clinical applications. In research settings, these lines serve as indispensable tools for elucidating molecular mechanisms involved in diseases where RTN1 is implicated. Clinically, they provide a potential pathway to discover novel interventions for conditions caused by RTN1 dysregulation, as well as aiding in drug development processes.
One distinct advantage of our RTN1 Gene Knockout Cell Lines is their consistency and reproducibility, which can be crucial for researchers. Unlike alternative methods that often suffer from variable results, our cell lines are validated to ensure stable and uniform knockout characteristics, allowing for accurate comparative studies. Additionally, they are compatible with various culture conditions, making them versatile tools for different experimental designs.
By choosing RTN1 Gene Knockout Cell Lines, researchers and clinicians gain a powerful asset for exploring gene function and its implications in health and disease. Our commitment to quality and innovation in biological products ensures that these cell lines meet the highest scientific standards, backed by extensive validation and technical support. Partner with us to advance your research with confidence as we strive to deliver exceptional tools that further scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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