Gene: RTCA
Official Full Name: RNA 3'-terminal phosphate cyclaseprovided by HGNC
Gene Summary: This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34001 | RTCA Knockout cell line (HeLa) | Human | RTCA | 1:3~1:6 | Negative | Online Inquiry |
KO34002 | RTCA Knockout cell line (HCT 116) | Human | RTCA | 1:2~1:4 | Negative | Online Inquiry |
KO34003 | RTCA Knockout cell line (HEK293) | Human | RTCA | 1:3~1:6 | Negative | Online Inquiry |
KO34004 | RTCA Knockout cell line (A549) | Human | RTCA | 1:3~1:4 | Negative | Online Inquiry |
RTCA Gene Knockout Cell Lines are precisely engineered cellular models that allow researchers to investigate gene function by systematically deactivating specific genes. Utilizing the CRISPR-Cas9 gene editing technology, these cell lines facilitate targeted gene deletion, enabling the study of gene-specific pathways and biological processes. By offering a controlled environment to observe the phenotypic consequences of gene disruption, RTCA Gene Knockout Cell Lines are invaluable in functional genomics research.
The key functions of RTCA Gene Knockout Cell Lines are centered around their ability to provide insights into gene interactions, disease mechanisms, and therapeutic targets. The CRISPR-Cas9 system introduces double-strand breaks at predetermined genomic loci, relying on the cell's natural repair mechanisms to introduce mutations that deactivate gene expression. This level of specificity ensures that the resulting knockout models mimic natural gene loss conditions, permitting more accurate modeling of disease states and helping to elucidate biological pathways.
Scientifically, these cell lines hold significant importance in both research and clinical settings. They are foundational tools in drug discovery, allowing for the identification of novel therapeutic targets, as well as in cancer research, where understanding gene function can influence treatment strategies. Moreover, they support a wide array of applications, such as the study of metabolic disorders and responses to environmental stressors.
The advantages of using RTCA Gene Knockout Cell Lines lie in their ease of use, reproducibility, and the efficiency of the CRISPR-Cas9 technology compared to traditional gene knockout methods. Unlike earlier techniques that often required lengthy and complex procedures, these cell lines enable faster results with high fidelity, making them superior for rapid experimentation and validation studies. Furthermore, their comprehensive resource availability—including technical support and data sharing—empowers researchers to maximize their experimental outcomes.
For researchers, clinicians, and biotechnology firms, RTCA Gene Knockout Cell Lines represent a transformative tool for advancing scientific discovery. By elucidating the roles of specific genes in health and disease, they provide critical insights that can lead to innovative treatment strategies and improved patient outcomes. Our company, with its commitment to excellence in developing high-quality biological products, offers these cell lines as part of a broader portfolio aimed at enhancing research capabilities and contributing to breakthroughs in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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