Gene: RSPO3
Official Full Name: R-spondin 3provided by HGNC
Gene Summary: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11681 | RSPO3 Knockout cell line (A549) | Human | RSPO3 | 1:3~1:4 | Negative | Online Inquiry |
RSPO3 Gene Knockout Cell Lines represent a cutting-edge innovation in cellular biology, engineered to provide researchers with a powerful tool for exploring the functions and pathological roles of the RSPO3 gene. RSPO3, or R-spondin 3, is a crucial modulator of the Wnt signaling pathway, which plays a significant role in various developmental processes and tissue regeneration. By creating targeted knockout cell lines, scientists can efficiently delete the RSPO3 gene, enabling the study of its effects on cellular proliferation, differentiation, and signaling dynamics in a controlled environment.
The primary mechanism underlying the utility of the RSPO3 Gene Knockout Cell Lines is their ability to provide insights into the gene's regulatory effects on the Wnt pathway. Studying these cell lines can elucidate the implications of RSPO3 in diseases characterized by aberrant Wnt signaling, such as cancer and various developmental disorders. Additionally, these cell lines can serve as valuable models for drug discovery and testing, offering platforms to assess potential therapeutic interventions that target the Wnt signaling cascade.
What sets RSPO3 Gene Knockout Cell Lines apart from other genetic manipulation tools is their high specificity and reliability, ensuring precise gene editing outcomes with minimal off-target effects. This is particularly advantageous over conventional methods that may yield variable results, thereby enhancing reproducibility in experimental settings.
For researchers and clinicians, the RSPO3 Gene Knockout Cell Lines offer exceptional opportunities to advance understanding in both basic and applied biological research. The ability to selectively inactivate RSPO3 provides insights that can lead to innovative therapeutic strategies and biomarkers for disease diagnosis and progression, which are critical for developing personalized medicine approaches.
With years of expertise in genetic engineering and a commitment to delivering high-quality biological products, our company is dedicated to supporting the research community’s efforts to unlock the complexities of cellular functions. We continually strive to provide innovative tools that enrich scientific discovery, thereby fostering advancements in healthcare and our understanding of human biology.
Please note that all services are for research use only. Not intended for any clinical use.
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