Gene: RRH
Official Full Name: retinal pigment epithelium-derived rhodopsin homologprovided by HGNC
Gene Summary: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31610 | RRH Knockout cell line (HCT 116) | Human | RRH | 1:2~1:4 | Negative | Online Inquiry |
RRH Gene Knockout Cell Lines are genetically modified cell lines specifically designed to have the retinoic acid receptor-related orphan receptor gene (RRH) disrupted or deleted. These cell lines serve as essential tools in molecular biology and genetic research, allowing scientists to study the function of the RRH gene and its associated pathways in cellular processes. Utilizing CRISPR-Cas9 or similar gene editing technologies, RRH Gene Knockout Cell Lines provide a precise and efficient method to create targeted modifications that can elucidate the role of this receptor in various physiological and pathological conditions.
The key functions of these cell lines revolve around understanding the molecular mechanisms regulated by RRH. This orphan receptor is known to influence gene expression linked to metabolism, cell differentiation, and response to environmental signals. By observing the effects of gene knockout, researchers can decipher the signaling pathways influenced by RRH, thereby gaining insights into its involvement in diseases such as cancer, metabolic disorders, and neurodegenerative conditions.
The scientific importance of RRH Gene Knockout Cell Lines is immense, as they offer valuable applications in both basic research and clinical settings. For instance, they can serve as a model for drug discovery, allowing for high-throughput screening of therapeutic compounds that target RRH-associated pathways. In clinical research, understanding the consequences of RRH gene disruption can pave the way for novel treatment strategies for diseases where its dysregulation is implicated.
Compared to alternatives, such as pharmacological inhibitors or non-specific knockdown techniques, the RRH Gene Knockout Cell Lines provide specificity and reliability. The knockout approach eliminates off-target effects, enabling researchers to draw more definitive conclusions about RRH’s role in biological systems.
For researchers and clinicians seeking to advance their understanding of gene function and its impact on health, these cell lines represent a robust and versatile resource. Their utility in dissecting complex biological processes underscores their value in progressing scientific knowledge and therapeutic development.
As a leader in the field of biological products, our company specializes in providing high-quality genetically engineered models tailored to meet the needs of today's scientific inquiries. Each product is developed with the utmost scientific rigor, reflecting our commitment to advancing research capabilities and therapeutic innovations.
Please note that all services are for research use only. Not intended for any clinical use.
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