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RPP25L Knockout Cell Lines

Gene: RPP25L

Official Full Name: ribonuclease P/MRP subunit p25 likeprovided by HGNC

Gene Summary: This gene encodes a protein that appears to belong to a family of evolutionarily related proteins (DUF78), that may share one or more domains in common. Members of this family are small archaebacterial proteins with no known function. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26315 RPP25L Knockout cell line (HeLa) Human RPP25L 1:3~1:6 Negative Online Inquiry
KO26316 RPP25L Knockout cell line (HCT 116) Human RPP25L 1:2~1:4 Negative Online Inquiry
KO26317 RPP25L Knockout cell line (HEK293) Human RPP25L 1:3~1:6 Negative Online Inquiry
KO26318 RPP25L Knockout cell line (A549) Human RPP25L 1:3~1:4 Negative Online Inquiry

Background

RPP25L Gene Knockout Cell Lines are specially engineered cellular models that have had the RPP25L gene functionally disrupted, facilitating the investigation of its biological roles and mechanisms. This targeted gene knockout allows researchers to evaluate the consequences of RPP25L deficiency on cellular processes, including development, apoptosis, and immune responses.

The functionality of RPP25L, also known as ribonuclease P/RNase MRP protein subunit P25, is primarily linked to its involvement in RNA processing, particularly in the generation of mature tRNA molecules. By inactivating this gene, scientists can explore the downstream effects on RNA metabolism and how these may contribute to various disease states or developmental anomalies. The mechanisms through which these cell lines operate are rooted in complementary gene editing techniques, predominantly CRISPR-Cas9 technology, which provides precise targeting and high efficiency compared to traditional knockout strategies.

The scientific significance of RPP25L Gene Knockout Cell Lines is profound, offering critical insights into genetic disorders and providing a platform for drug discovery and therapeutic interventions in clinical settings. Their application spans from fundamental research on gene function to translational studies that aim to elucidate the molecular basis of diseases linked to RPP25L dysfunction.

One of the key advantages of using RPP25L Gene Knockout Cell Lines over alternative models is their enhanced specificity and reproducibility in studies focused on gene function. Other models may introduce off-target effects or fail to fully mimic physiological responses due to their inherent complexities. In contrast, these knockout lines offer a streamlined approach to dissect cellular mechanisms, allowing for more straightforward interpretation of experimental outcomes.

For researchers and clinicians alike, the value of RPP25L Gene Knockout Cell Lines is underscored by their potential to accelerate discoveries and facilitate the development of novel therapeutic strategies. Our company is dedicated to advancing biological research, providing high-quality model systems that support innovative scientific explorations and enable breakthroughs in medicine. By offering these specialized bioengineered cell lines, we stand at the forefront of molecular biology and genetic research, ensuring our clients have access to tools that are critical for advancing their studies.

Please note that all services are for research use only. Not intended for any clinical use.

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