Gene: RNF185
Official Full Name: ring finger protein 185provided by HGNC
Gene Summary: Enables ubiquitin binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Involved in several processes, including positive regulation of ERAD pathway; protein ubiquitination; and proteolysis involved in protein catabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04386 | RNF185 Knockout cell line (HeLa) | Human | RNF185 | 1:3~1:6 | Negative | Online Inquiry |
KO04387 | RNF185 Knockout cell line (HCT 116) | Human | RNF185 | 1:2~1:4 | Negative | Online Inquiry |
KO04388 | RNF185 Knockout cell line (HEK293) | Human | RNF185 | 1:3~1:6 | Negative | Online Inquiry |
KO04389 | RNF185 Knockout cell line (A549) | Human | RNF185 | 1:3~1:4 | Negative | Online Inquiry |
RNF185 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to lack the RNF185 gene, a crucial component in various cellular signaling pathways and processes. This product serves as an integral tool for scientists investigating the role of RNF185 in cellular functions such as growth regulation, apoptosis, and immune responses. The knockout of this gene enables researchers to discern its specific contributions to pathological conditions, facilitating a deeper understanding of related diseases.
The key function of RNF185 Gene Knockout Cell Lines lies in their ability to allow precise functional studies of the RNF185 gene's role. By eliminating this gene, researchers can explore alterations in cellular behaviors, signaling cascades, and phenotypic changes. Mechanistically, the absence of RNF185 can influence ubiquitination processes and protein stability, offering insights into its involvement in ubiquitin-mediated pathways, which are pivotal in regulating various key cellular functions.
The scientific importance of RNF185 knockout lines extends to both basic research and clinical applications. They can be utilized to investigate the mechanisms underlying diseases such as cancer, autoimmune disorders, and metabolic syndromes, thus contributing to the development of targeted therapeutic strategies. Additionally, RNF185 Gene Knockout Cell Lines serve as platforms for drug screening and biomarker discovery, making them indispensable in the field of translational medicine.
When compared to alternative models, these knockout cell lines provide enhanced specificity and accuracy in evaluating the role of RNF185 without the confounding influences present in wild-type cells. Moreover, researchers can benefit from consistent cell lines tailored for reproducibility, ensuring robust and reliable experimental outcomes.
Researchers and clinicians seeking to advance their understanding of gene-function relationships or uncover new therapeutic targets will find RNF185 Gene Knockout Cell Lines invaluable. Their unique design fosters groundbreaking discoveries that could bridge gaps in current scientific knowledge and promote advances in precision medicine.
With years of expertise in the development of innovative biological research products, our company is dedicated to empowering scientists with cutting-edge tools tailored to meet the evolving needs of the research community. By choosing our RNF185 Gene Knockout Cell Lines, users gain access to a high-quality resource that can significantly accelerate their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.