Gene: RNF11
Official Full Name: ring finger protein 11provided by HGNC
Gene Summary: The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN). [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27917 | RNF11 Knockout cell line (HeLa) | Human | RNF11 | 1:3~1:6 | Negative | Online Inquiry |
KO27918 | RNF11 Knockout cell line (HCT 116) | Human | RNF11 | 1:2~1:4 | Negative | Online Inquiry |
KO27919 | RNF11 Knockout cell line (HEK293) | Human | RNF11 | 1:3~1:6 | Negative | Online Inquiry |
KO27920 | RNF11 Knockout cell line (A549) | Human | RNF11 | 1:3~1:4 | Negative | Online Inquiry |
RNF11 Gene Knockout Cell Lines represent a pioneering advancement in the field of genetic research and cellular biology. These specially engineered cell lines feature a targeted knockout of the RNF11 gene, which encodes for a RING finger protein involved in various cellular processes, including protein degradation and cell signaling. By disrupting the RNF11 gene, researchers can investigate the functional roles of this protein in diverse biological contexts, enabling a deeper understanding of cellular mechanisms and disease pathology.
The key function of RNF11 Gene Knockout Cell Lines lies in their ability to elucidate the role of RNF11 in regulating ubiquitin-mediated proteolysis and its impact on downstream signaling pathways. By comparing these knockout cells to wild-type controls, scientists can dissect cellular responses to stimuli, observe alterations in protein expression profiles, and examine changes in cellular metabolism and proliferative capacity. This versatile tool can facilitate the study of various conditions, including cancer, neurodegenerative disorders, and immune responses, where RNF11’s involvement may be critical.
The scientific importance of these cell lines extends to both research and clinical settings. They provide a reliable model to explore the therapeutic potential of targeting RNF11 or its associated pathways, supporting drug discovery initiatives aimed at modulating these processes for clinical benefit. Furthermore, these cell lines can serve as a platform for high-throughput screening of compounds, paving the way for innovative treatment strategies.
Compared to alternative cell models that may be limited in their ability to mimic the precise effects of RNF11 loss, our RNF11 Gene Knockout Cell Lines offer a more accurate representation of gene function. They are meticulously validated for consistent performance in various assays and feature easy-to-use formats that integrate seamlessly into existing workflows.
This product is invaluable to researchers and clinicians seeking groundbreaking insights into cellular function and disease mechanisms, providing a robust tool for understanding the implications of RNF11 deficiency. By choosing our RNF11 Gene Knockout Cell Lines, users can leverage our extensive expertise in genetic engineering and cell line development to advance their research efforts with confidence.
Our company stands at the forefront of biotechnological innovation, committed to delivering high-quality biological products that empower researchers to make significant strides in their scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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