Gene: RERE
Official Full Name: arginine-glutamic acid dipeptide repeatsprovided by HGNC
Gene Summary: This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38887 | RERE Knockout cell line (HeLa) | Human | RERE | 1:3~1:6 | Negative | Online Inquiry |
KO38888 | RERE Knockout cell line (HCT 116) | Human | RERE | 1:2~1:4 | Negative | Online Inquiry |
KO38889 | RERE Knockout cell line (HEK293) | Human | RERE | 1:3~1:6 | Negative | Online Inquiry |
KO38890 | RERE Knockout cell line (A549) | Human | RERE | 1:3~1:4 | Negative | Online Inquiry |
RERE Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the biological functions of the RERE gene, known for its role in various cellular processes, including transcriptional regulation and development. By employing CRISPR-Cas9 technology or similar gene editing methods, these cell lines have been precisely modified to eliminate the RERE gene, allowing researchers to elucidate its contributions to cellular behavior, pathways, and related disease mechanisms.
The key function of these knockout cell lines is to enable detailed investigations into the phenotypic alterations resulting from the absence of the RERE gene. This involves analyzing changes in gene expression profiles, cellular proliferation, differentiation, and response to external stimuli. Researchers can leverage these models to explore the implications of RERE deficiency in various contexts, such as cancer biology and developmental disorders, thereby enhancing our understanding of its role in health and disease.
Scientifically, RERE Gene Knockout Cell Lines hold immense importance in both research and clinical settings. They provide valuable tools for drug discovery, biomarker identification, and the development of targeted therapies, serving as a platform for high-throughput screening and functional assays. The specificity of these knockouts allows for more accurate results compared to traditional techniques, making them especially advantageous in elucidating gene function.
What sets our RERE Gene Knockout Cell Lines apart from alternatives is the rigor of our validation processes and the precision of our gene-editing techniques. Each cell line is extensively characterized to ensure consistent performance and reliable results, significantly reducing variability in experimental outcomes. Our commitment to quality and reproducibility ensures that researchers and clinicians can trust our products in their critical work.
For researchers and clinicians aiming to uncover fundamental biological insights or develop innovative therapeutics, RERE Gene Knockout Cell Lines represent an invaluable asset. With the promise of advancing their research capabilities, they are a strategic choice for rigorous scientific exploration. Our company prides itself on being at the forefront of biotechnological advancements, providing a portfolio of products that empower the scientific community to push the boundaries of knowledge and therapeutic possibilities.
Please note that all services are for research use only. Not intended for any clinical use.
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