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RCHY1 Knockout Cell Lines

Gene: RCHY1

Official Full Name: ring finger and CHY zinc finger domain containing 1provided by HGNC

Gene Summary: The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28663 RCHY1 Knockout cell line (HeLa) Human RCHY1 1:3~1:6 Negative Online Inquiry
KO28664 RCHY1 Knockout cell line (HCT 116) Human RCHY1 1:2~1:4 Negative Online Inquiry
KO28665 RCHY1 Knockout cell line (HEK293) Human RCHY1 1:3~1:6 Negative Online Inquiry
KO28666 RCHY1 Knockout cell line (A549) Human RCHY1 1:3~1:4 Negative Online Inquiry

Background

RCHY1 Gene Knockout Cell Lines are genetically modified cellular systems in which the RCHY1 gene has been selectively disrupted, allowing researchers to investigate the gene’s role in various biological processes. The knockout methodology utilizes CRISPR-Cas9 gene editing technology to achieve precise deletions, thereby creating a model that mimics the loss of gene function observed in certain diseases or biological conditions. These cell lines serve as important tools for elucidating the pathways influenced by RCHY1 and how alterations in its expression can impact cellular behavior.

The primary function of RCHY1 is linked to protein ubiquitination, which plays a crucial role in regulating protein degradation, cell signaling, and various other cellular processes. By studying knockout models, scientists can unravel the implications of RCHY1 underexpression or loss and its contributions to cellular homeostasis and disease progression.

In research and clinical settings, RCHY1 Gene Knockout Cell Lines provide valuable insights into oncogenic signaling pathways and potential therapeutic targets. Their applications extend to drug development, biomarker identification, and the investigation of gene-environment interactions that can govern disease phenotypes.

What sets our RCHY1 Gene Knockout Cell Lines apart from alternatives is our commitment to quality and reproducibility. Each cell line is thoroughly characterized to ensure stability and uniformity across experiments. Additionally, they provide rapid results, enabling researchers to streamline their workflow without compromising data integrity.

By incorporating our RCHY1 Gene Knockout Cell Lines into their research, scientists and clinicians can accelerate discoveries that hinge on understanding the genetic underpinnings of diseases. Our company, with its rich expertise in gene editing technologies and extensive support services, is dedicated to empowering researchers with high-quality, reliable biological tools that drive innovative science forward.

Please note that all services are for research use only. Not intended for any clinical use.

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