Gene: RBSN
Official Full Name: rabenosyn, RAB effectorprovided by HGNC
Gene Summary: This gene encodes a protein that belongs to the FYVE zinc finger family of proteins. The encoded protein interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in this gene is associated with a defect in the early endocytic pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14646 | RBSN Knockout cell line (HeLa) | Human | RBSN | 1:3~1:6 | Negative | Online Inquiry |
KO14647 | RBSN Knockout cell line (HCT 116) | Human | RBSN | 1:2~1:4 | Negative | Online Inquiry |
KO14648 | RBSN Knockout cell line (HEK293) | Human | RBSN | 1:3~1:6 | Negative | Online Inquiry |
KO14649 | RBSN Knockout cell line (A549) | Human | RBSN | 1:3~1:4 | Negative | Online Inquiry |
RBSN Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of the RBSN (Receptor-Binding Serine/Threonine Kinase N) gene by completely abrogating its functional expression. These knockout cell lines are developed using advanced CRISPR-Cas9 genome editing technology, which allows for precise modifications within the genome, ensuring that the RBSN gene is effectively silenced. By creating a model that lacks the RBSN gene, researchers can delve into its biological roles, interactions, and pathways, as well as understand the implications of RBSN dysregulation in various diseases, including cancer and neurodegenerative disorders.
The primary mechanism by which RBSN Gene Knockout Cell Lines operate is through the disruption of the RBSN gene's coding sequence, leading to the production of non-functional or truncated protein products. This allows for the investigation of the signaling pathways and cellular processes that rely on RBSN, providing insights into its role in cell proliferation, differentiation, and apoptosis. Such functional studies are crucial for identifying potential therapeutic targets and developing novel strategies in clinical research.
The scientific importance of RBSN Gene Knockout Cell Lines cannot be overstated; they serve as invaluable tools in both basic and applied research settings. These models enable scientists to study gene function in a controlled environment, facilitating high-throughput screening assays and allowing for the testing of therapeutic compounds. Compared to traditional cell models, the knockout approach significantly increases the specificity of experimental results, enabling a better understanding of gene networks.
Advantages of RBSN Gene Knockout Cell Lines include their robustness and reproducibility, as well as their versatility for use in various types of assays, such as drug responses, pathway analysis, and gene expression profiling. This product also offers a unique selling point by providing researchers with ready-to-use cell lines that save time on initial experimental design and setup.
For researchers and clinicians seeking reliable and innovative solutions in gene function studies, RBSN Gene Knockout Cell Lines offer essential advantages that drive progress in understanding complex biological systems. Our company is committed to delivering high-quality genetic models, underpinned by our expertise in molecular biology and genomic technologies, ensuring that researchers have access to the tools they need to advance their work effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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