Home / RASD2 Knockout Cell Lines

RASD2 Knockout Cell Lines

Gene: RASD2

Official Full Name: RASD family member 2provided by HGNC

Gene Summary: This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29150 RASD2 Knockout cell line (A549) Human RASD2 1:3~1:4 Negative Online Inquiry

Background

RASD2 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the RASD2 gene's role in various biological processes and disease mechanisms. This product specifically involves the targeted deletion of the RASD2 gene, a member of the RAS superfamily of GTPases, which is implicated in cellular signaling pathways that regulate growth, differentiation, and survival. By employing CRISPR/Cas9 technology or other gene-editing techniques, RASD2 Gene Knockout Cell Lines provide a powerful tool for researchers to dissect gene function and explore the consequences of RASD2 loss on cellular behavior.

The key functionality of these knockout cell lines lies in their utility as a state-of-the-art model system for investigating the biological significance of RASD2. Researchers can examine altered signaling pathways, assess changes in cellular morphology, and evaluate shifts in proliferation, migration, or apoptosis. This is particularly crucial in understanding RASD2's involvement in cancer, neurological disorders, and other pathologies.

In both research and clinical settings, the RASD2 Gene Knockout Cell Lines serve as foundational tools for drug discovery and therapeutic development. By elucidating the molecular pathways involving RASD2, these cell lines can aid in identifying novel targets for interventions and validate potential candidates for better clinical outcomes.

What distinguishes our RASD2 Gene Knockout Cell Lines from alternatives is the rigor of our engineering processes and the specificity of our targeting approach, which reduces off-target effects and increases the reliability of experimental results. Additionally, our cell lines are validated for high efficiency and reproducibility in a range of assays.

For researchers and clinicians alike, the value of the RASD2 Gene Knockout Cell Lines is underscored by their ability to drive innovation and discovery in the study of cellular functions and disease mechanisms. By utilizing these superior models, users can significantly enhance the quality and depth of their research initiatives.

Our company is committed to advancing scientific research through high-quality biological products, combining expertise with state-of-the-art techniques to offer reliable and innovative tools tailored to the needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.