Gene: RANBP10
Official Full Name: RAN binding protein 10provided by HGNC
Gene Summary: RAN is a small GTPase involved in the assembly of microtubules to form mitotic spindles. The protein encoded by this gene is a cytoplasmic guanine nucleotide exchange factor (GEF) that binds beta-tubulin and has GEF activity toward RAN. The encoded protein plays a role in the formation of noncentrosomal microtubules. In addition, this protein may be involved in the regulation of D(1) receptor signaling by protein kinase C delta and protein kinase C gamma. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14717 | RANBP10 Knockout cell line (HeLa) | Human | RANBP10 | 1:3~1:6 | Negative | Online Inquiry |
KO14718 | RANBP10 Knockout cell line (HCT 116) | Human | RANBP10 | 1:2~1:4 | Negative | Online Inquiry |
KO14719 | RANBP10 Knockout cell line (HEK293) | Human | RANBP10 | 1:3~1:6 | Negative | Online Inquiry |
KO14720 | RANBP10 Knockout cell line (A549) | Human | RANBP10 | 1:3~1:4 | Negative | Online Inquiry |
RANBP10 Gene Knockout Cell Lines are genetically engineered cell models in which the RANBP10 gene has been deliberately disrupted or knocked out. This innovative tool is crucial for researchers studying the biological functions of the RANBP10 protein, known to play significant roles in RNA export, cellular signaling, and various aspects of cell cycle regulation. By eliminating the functionality of this gene, these knockout cell lines facilitate the investigation of the gene's impact on cellular processes, enabling detailed analysis of its role in health and disease.
The primary mechanism underlying RANBP10 gene knockout involves the application of CRISPR-Cas9 technology or other gene editing approaches to create precise deletions or mutations within the gene sequence. This targeted gene disruption provides a clearer understanding of the protein's contributions to biological pathways, aiding researchers in deciphering its involvement in oncogenesis, viral infections, and auditory function, among other areas.
The scientific importance of RANBP10 Gene Knockout Cell Lines is underpinned by their wide-ranging applications in both basic and applied research. In preclinical studies, these models offer exceptional value in drug discovery, toxicology, and therapeutic development, helping to elucidate target-specific mechanisms and biomarker identification. Using these cell lines, researchers can dissect the influence of RANBP10 on cellular responses, providing invaluable insights that can lead to novel therapeutic strategies.
Compared to traditional cell lines, the RANBP10 Gene Knockout Cell Lines stand out for their specificity and relevance, enabling more reliable and reproducible data in experiments that investigate the gene's functional consequences. Additionally, the establishment of multiple knockout variants can help in accommodating diverse research objectives, from pathway analysis to high-throughput screening.
For researchers, clinicians, and biopharmaceutical companies aiming to enhance their understanding of genetic interactions and potential therapeutic targets, RANBP10 Gene Knockout Cell Lines offer a robust solution. Their ability to deliver precise and actionable data makes them an essential asset in advancing biomedical research and clinical applications.
With years of expertise in developing tailored biological products, our company is dedicated to supporting the scientific community with cutting-edge tools that expand research capabilities and foster innovative discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.